Compare Aceon vs. felodipine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Aceon (perindopril)

Prescription only

Plendil (felodipine)

Prescription only
Lowers blood pressure.

Aceon (perindopril) is a good blood pressure-lowering medicine that protects kidney function.

Lowers blood pressure.

Plendil (felodipine) works well to lower blood pressure, but it may cause swelling in your arms and legs at higher doses.

Upsides
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or who have mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Plendil (felodipine) is a good option for people with high blood pressure.
  • Calcium channel blockers sometimes work better for people of African descent than other blood pressure lowering drugs.
Downsides
  • Up to 1 in 10 people can get a dry cough with this class of medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • May be more expensive than other drugs in its class.
  • Plendil (felodipine) may not work as well as other calcium channel blockers.
  • It can lead to more swelling in your arms and legs when taken at higher doses.
  • You can't miss doses. Stopping Plendil (felodipine) could cause a sudden spike in blood pressure.
  • Plendil (felodipine) can't be crushed or cut into two.
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Used for
Dosage forms
  • Pill
  • Extended release
Price
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Reviews
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Side effects
The Aceon (perindopril) FDA package insert doesn’t have numbers about how common side effects are.
8possible side effects
  • Headache
    10%
  • Swelling
    9%
  • Flushing
    5%
  • Racing heart beat
    4%
  • Weakness
    3%
  • Dizziness
    3%
  • Nausea
    2%
  • Colds or flu
    2%
See more detailed side effects
Risks and risk factors
  • Harm to fetus
    • Women of childbearing age
  • Cough
    • History of ACE inhibitor induced cough
  • Swelling of face and head
    • African descent
  • High potassium
    • Current kidney problems
    • Taking other medicines that increase potassium
    • Use of salt substitutes
  • Worsening kidney problems
    • History of kidney problems
  • Low blood pressure
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
See more detailed risks and warnings
  • Low blood pressure
    • Over age 65
  • Heart failure
    • Taking in combination with a beta-blocker
  • Special dosing requirements
    • Liver disease
    • Over age 65
  • Swelling in arms and legs
    • History of heart failure
    • History of kidney disease
See more detailed risks and warnings