Compare Aciphex vs. Pepcid
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats heartburn and ulcers.
Aciphex (rabeprazole) is good for treating heartburn and ulcers, but should not be used long-term.
Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids.
3.7/ 5 average rating with 853 reviewsforPepcid
- Aciphex (rabeprazole) works better than over-the-counter medications that have not relieved your acid reflux.
- The delayed-release pill provides relief over 24 hours.
- Aciphex (rabeprazole) can be taken with or without food.
- The capsule can be safely used by children as young as 1 year old.
- Most people can take Famotidine without any noticeable day-to-day side effects.
- Famotidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
- You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
- Available as both a generic and over-the-counter option, so it's pretty affordable.
- Few drug interactions.
- Using Aciphex (rabeprazole) for a long time can can weaken your bones or increase your risk for infectious diarrhea.
- Lowers magnesium and vitamin B12 in your body so you may need to take supplements.
- Aciphex (rabeprazole) interferes with how many medications work.
- Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Famotidine.
- Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Famotidine (H2 blockers).
- Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
- Acid Reflux
- Stomach ulcers
- Delayed release pill
- Chewable tablet
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5possible side effects
- Abdominal pain4%
2possible side effects
Risks and risk factors
- Stomach cancer
- Kidney inflammation
- Severe diarrhea
- Being hospitalized
- Antibiotic use
- Bone fractures
- High dose Aciphex (rabeprazole)
- Taking Aciphex (rabeprazole) for longer than one year
- Low bone mineral density
- Age 50 years or older
- Taking steroids or anti-seizure medicines
- Low levels of magnesium and vitamin B12
- Hiding possible cancer
- Increased side effects
- Current kidney disease
- Allergic reaction