Compare Aciphex vs. Prevacid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT

Aciphex (rabeprazole)

Prescription only

Prevacid (lansoprazole)

Prescription or OTC
Treats heartburn and ulcers.

Aciphex (rabeprazole) is good for treating heartburn and ulcers, but should not be used long-term.

Treats heartburn and stomach ulcers.

Prevacid (lansoprazole) is an effective and inexpensive acid reducer commonly used to provide heartburn relief and help heal ulcers.

●●●●●
4.0/ 5 average rating with 21 reviewsforPrevacid
Upsides
  • Aciphex (rabeprazole) works better than over-the-counter medications that have not relieved your acid reflux.
  • The delayed-release pill provides relief over 24 hours.
  • Aciphex (rabeprazole) can be taken with or without food.
  • The capsule can be safely used by children as young as 1 year old.
  • Most people can take Prevacid (lansoprazole) without any noticeable day-to-day side effects.
  • Comes in a dissolving tablet to be placed on the tongue if you cannot or do not like to swallow pills.
  • Prevacid (lansoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Prevacid (lansoprazole) is available over-the-counter and as inexpensive, generic options.
Downsides
  • Using Aciphex (rabeprazole) for a long time can can weaken your bones or increase your risk for infectious diarrhea.
  • Lowers magnesium and vitamin B12 in your body so you may need to take supplements.
  • Aciphex (rabeprazole) interferes with how many medications work.
  • Doesn't start working right away like some other acid reducers (Tums, Rolaids, or Maalox).
  • May not be the best choice for patients 65 years of age and older due to risk of bone fractures and C. diff infection (bacterial).
  • Is used if you have frequent heartburns that occur more than 2 days per week. Speak to your doctor or pharmacist if you only have occasional heartburn.
ADVERTISEMENT
Used for
Dosage forms
  • Delayed release pill
  • Extended release
  • Dissolving tablet extended release
  • Liquid
Price
Lowest price
$13.00
Find instant savings near you
Lowest price
$19.00
Find instant savings near you
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
Not enough review data.Leave a review
21 reviews so far
71%
saidit'sworth it
71%
saiditworked well
19%
saidit'sa big hassle

Have you used Prevacid (lansoprazole)?

Leave a review
Side effects
5possible side effects
  • Headache
    10%
  • Diarrhea
    5%
  • Nausea
    5%
  • Vomiting
    4%
  • Abdominal pain
    4%
See more detailed side effects
2possible side effects
  • Diarrhea
    4%
  • Abdominal pain
    2%
See more detailed side effects
Risks and risk factors
  • Stomach cancer
  • Kidney inflammation
  • Severe diarrhea
    • Being hospitalized
    • Antibiotic use
  • Bone fractures
    • High dose Aciphex (rabeprazole)
    • Taking Aciphex (rabeprazole) for longer than one year
    • Low bone mineral density
    • Age 50 years or older
    • Alcohol
    • Smoking
    • Taking steroids or anti-seizure medicines
  • Low levels of magnesium and vitamin B12
  • Lupus
See more detailed risks and warnings
  • Stomach cancer
  • Acute kidney damage
  • Clostridium difficile associated diarrhea (CDAD)
  • Bone fractures
    • High dose Prevacid (lansoprazole)
    • Long-term treatment with Prevacid (lansoprazole)
    • Low bone mineral density
    • Older age
  • Lupus
  • Low vitamin or mineral levels
See more detailed risks and warnings
Learn more about Aciphex (rabeprazole)
Learn more about Prevacid (lansoprazole)