Compare Adlyxin vs. Byetta

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Adlyxin (lixisenatide)

Prescription only

Byetta (Exenatide)

Prescription only
Lowers blood sugar.

Adlyxin (lixisenatide) can lower blood sugar in addition to metformin, but it must be injected and usually causes upset stomach.

Lowers blood sugar.

Byetta (Exenatide) can lower your blood sugars in addition to metformin. It does not increase your appetite unlike some other anti-diabetics, but must be given by injection and usually causes upset stomach.

Upsides
  • Lowers A1c (average blood sugar over time) up to 1%.
  • Not as likely to cause very low blood sugar as glyburide or insulin.
  • Adlyxin (lixisenatide) is injected once daily.
  • Adlyxin (lixisenatide) comes as a pre-filled injectable pen that does not require you to measure the dose, so you may find this more convenient than other types of injections.
  • Can lower your A1c (average blood sugar over time) by 1%.
  • Not as likely to cause very low blood sugar as glyburine or insulin.
  • Does not increase your appetite like other anti-diabetic medicines.
  • Pen is dialed to a single dose for easy injections.
Downsides
  • Not good enough by itself if you have really high blood sugars. It needs to be combined with other oral anti-diabetic medicines or insulin.
  • Commonly causes upset stomach.
  • Can affect how well your birth control pills work. Take 1 hour before or 11 hours after injecting Adlyxin (lixisenatide).
  • Oral diabetes medicines work just as well and are cheaper.
  • Byetta (Exenatide) must be injected twice a day. Other medicines like it can be injected once daily or even weekly.
  • It commonly causes nausea, vomiting, diarrhea, constipation, or indigestion.
  • Can affect how well your antibiotics and birth control pills work. Take them no sooner than one hour after your injections.
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Used for
Dosage forms
  • Injection
  • Injection
Price
Lowest price
$645.23
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Lowest price
$725.87
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Reviews
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Side effects
10possible side effects
  • Stomach discomfort
    40%
  • Nausea
    25%
  • Vomiting
    10%
  • Headache
    9%
  • Diarrhea
    8%
  • Dizziness
    7%
  • Injection site reaction
    4%
  • Upset stomach
    3%
  • Constipation
    3%
  • Signs of low blood sugar
    2%
See more detailed side effects
3possible side effects
  • Nausea
    8%
  • Vomiting
    4%
  • Upset stomach
    3%
See more detailed side effects
Risks and risk factors
  • Loss of effectiveness
  • Inflammation of pancreas (pancreatitis)
    • History of pancreatitis
    • History of gallstones
    • alcoholism
    • Elevated triglycerides
  • Severe allergic reactions
  • Kidney damage
    • Several renal impairment
    • End-stage renal disease
    • Kidney problems
    • dehydration
  • Low blood sugar (hypoglycemia)
    • Use of insulin(s)
    • Use of insulin-secreting medicines
  • Overexposure to other drugs
    • Severe gastrointestinal disease
    • Gastroparesis
See more detailed risks and warnings
  • Loss of medication effectiveness
  • Pancreatitis
  • Kidney problems
    • Severe renal impairment
    • End-stage renal disease
  • Serious stomach problems
    • Severe gastrointestinal disease
    • Gastroparesis
  • Low blood sugar (hypoglycemia)
See more detailed risks and warnings
Learn more about Adlyxin (lixisenatide)
Learn more about Byetta (Exenatide)