Compare Adlyxin vs. Trulicity
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood sugar.
Adlyxin (lixisenatide) can lower blood sugar in addition to metformin, but it must be injected and usually causes upset stomach.
Lowers your blood sugar.
Trulicity (dulaglutide) is a once-weekly injectable medicine that's used to control diabetes, but it can be expensive.
Upsides
- Lowers A1c (average blood sugar over time) up to 1%.
- Not as likely to cause very low blood sugar as glyburide or insulin.
- Adlyxin (lixisenatide) is injected once daily.
- Adlyxin (lixisenatide) comes as a pre-filled injectable pen that does not require you to measure the dose, so you may find this more convenient than other types of injections.
- Lowers A1c (average blood sugar over time) up to 1.5%.
- May help with weight loss and controling appetite.
- No limitation for people with kidney problems, but close monitoring is recommended.
- Dosed once a week compared to other injectables that have to be done daily.
- Medicine is ready to use, without need to mix.
Downsides
- Not good enough by itself if you have really high blood sugars. It needs to be combined with other oral anti-diabetic medicines or insulin.
- Commonly causes upset stomach.
- Can affect how well your birth control pills work. Take 1 hour before or 11 hours after injecting Adlyxin (lixisenatide).
- Oral diabetes medicines work just as well and are cheaper.
- Only available as an injection.
- Brand name medicine and can be expensive.
- Many people taking Trulicity (dulaglutide) have upset stomach and side effects like nausea, vomiting, diarrhea, constipation, or indigestion.
Used for
Dosage forms
- Injection
- Injection
Price
Lowest price
$676.08
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$734.81
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Side effects
10possible side effects
- Stomach discomfort40%
- Nausea25%
- Vomiting10%
- Headache9%
- Diarrhea8%
- Dizziness7%
- Injection site reaction4%
- Upset stomach3%
- Constipation3%
- Signs of low blood sugar2%
10possible side effects
- Low blood sugar35%
- Nausea21%
- Diarrhea13%
- Vomiting13%
- Stomach pain9%
- Low appetite9%
- Indigestion6%
- Tiredness6%
- Constipation4%
- Acid reflux2%
Risks and risk factors
- Loss of effectiveness
- Inflammation of pancreas (pancreatitis)
- History of pancreatitis
- History of gallstones
- alcoholism
- Elevated triglycerides
- Severe allergic reactions
- Kidney damage
- Several renal impairment
- End-stage renal disease
- Kidney problems
- dehydration
- Low blood sugar (hypoglycemia)
- Use of insulin(s)
- Use of insulin-secreting medicines
- Overexposure to other drugs
- Severe gastrointestinal disease
- Gastroparesis
- Thyroid cancer
- History of MTC
- History of MEN 2
- inflammation of pancreas (pancreatitis)
- History of pancreatitis
- History of gallstones
- alcoholism
- Elevated triglycerides
- Severe allergic reactions
- Kidney damage
- Kidney problems
- dehydration
- Low blood sugar (hypoglycemia)
- Use of insulin(s)
- Use of insulin-secreting medicines.
- Severe stomach problems
- Stomach or digestive tract disease
- Gastroparesis