Compare Advair vs. Combivent

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Prevents breathing problems.

Advair (fluticasone / salmeterol) combines two medicines into one inhaler, but it might be expensive.

3.8/ 5 average rating with 799 reviewsforAdvair
Makes it easier to breathe.

Combivent (ipratropium / albuterol) is effective for people who need 2 medications to control their COPD symptoms, but has to be used 4 times a day.

3.4/ 5 average rating with 142 reviewsforCombivent
Upsides
  • 2-in-1 medicine is more effective together than alone.
  • The diskus is used to treat both COPD and asthma.
  • Effectively relieves symptoms of COPD.
  • The Respimat inhaler doesn't require shaking before use, and only 1 inhalation per dose is needed.
  • The nebulizer solution comes in a generic form and is much cheaper than the inhaler.
Downsides
  • Take it daily and consistently for the best results. It is not for on-demand treatment of wheezing or asthma attacks.
  • Rinse your mouth with water after each inhalation to avoid fungal infections of the mouth.
  • No generic form of the inhaler is currently available, so it can be very expensive for people without insurance.
  • Can make your heart beat faster, which is an uncomfortable side effect. Might not be a good option for those with heart problems since the medicine can raise your heart rate and blood pressure.
  • Can raise eye pressure and worsen symptoms for people who have a certain type of glaucoma.
  • Can cause problems with urinating, so might not be appropriate for those with an enlarged prostate.
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Used for
Dosage forms
  • Inhaler
  • Inhaler
  • Nebulizer solution
Price
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Reviews
799 reviews so far
66%
saidit'sworth it
48%
saiditworked well
11%
saidit'sa big hassle

Have you used Advair (fluticasone / salmeterol)?

Leave a review
142 reviews so far
63%
saidit'sworth it
37%
saiditworked well
13%
saidit'sa big hassle

Have you used Combivent (ipratropium / albuterol)?

Leave a review
Side effects
15possible side effects
  • Lung infection
    27%
  • Sore throat
    13%
  • Headaches
    12%
  • Lung inflammation
    7%
  • Hoarseness
    5%
  • Sinus inflammation
    4%
  • Colds and flu
    4%
  • Nausea and vomiting
    4%
  • Stomach upset
    4%
  • Diarrhea
    4%
  • Muscle and joint pain
    4%
  • Stomach flu
    3%
  • Fungal infections
    3%
  • Cough
    3%
  • Bronchitis
    2%
See more detailed side effects
11possible side effects
  • Lung disease
    6%
  • Common cold symptoms
    4%
  • Sore throat
    4%
  • Cough
    3%
  • Headache
    3%
  • Inflammation of lung airways
    3%
  • Infection of airways, nose, and throat
    3%
  • Chest pain
    3%
  • Shortness of breath
    2%
  • Diarrhea
    2%
  • Urinary tract infection
    2%
See more detailed side effects
Risks and risk factors
  • Increased risk of death
    • Asthma
    • Children under 18
  • Increased risk of infections
    • History of chronic obstructive pulmonary disease (COPD)
    • COPD includes chronic bronchitis and emphysema
    • Age greater than 65 years
  • Mouth and throat infection
    • Not rinsing mouth after use
    • Higher dose of the corticosteroid medication contained in Advair (fluticasone / salmeterol)
  • Asthma attack
  • Heart disease
    • High blood pressure
    • Heart failure
    • Heart beat problems
    • Taking more Advair (fluticasone / salmeterol) than recommended
  • Serious allergic reaction
    • Milk allergy
See more detailed risks and warnings
  • Sudden-onset difficulty breathing
  • Effects on heart
    • Using more Combivent (ipratropium / albuterol) than recommended
    • People with heart problems
    • People with high blood pressure
    • People with an overactive thyroid
  • Effects on eyes
    • People with a history of narrow-angle glaucoma
  • Difficulty urinating
    • People with a history of urinary blockage
    • People with an enlarged prostate
  • Severe allergic reaction
  • Life-threatening effects
    • Using more Combivent (ipratropium / albuterol) than recommended
See more detailed risks and warnings