Compare Advair vs. Singulair

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT
Prevents breathing problems.

Advair (fluticasone / salmeterol) combines two medicines into one inhaler, but it might be expensive.

3.8/ 5 average rating with 799 reviewsforAdvair
Makes it easier to breathe.

Singulair (montelukast) has fewer side effects but doesn't work as well as some inhaled medications for asthma and allergies.

3.7/ 5 average rating with 557 reviewsforSingulair
Upsides
  • 2-in-1 medicine is more effective together than alone.
  • The diskus is used to treat both COPD and asthma.
  • Although not a first-line treatment, Singulair (montelukast) can effectively help children and adults with their asthma and allergies.
  • You only need to take it once a day.
  • Available as chewable tablets or granules that you can mix with food.
  • Singulair (montelukast) has fewer side effects than inhaled medications.
Downsides
  • Take it daily and consistently for the best results. It is not for on-demand treatment of wheezing or asthma attacks.
  • Rinse your mouth with water after each inhalation to avoid fungal infections of the mouth.
  • Even as a generic, Singulair (montelukast) is still expensive.
  • May not be a good choice if you have a history of mental conditions.
  • Singulair (montelukast) can't be used as a rescue inhaler if you get an asthma attack.
ADVERTISEMENT
Used for
Dosage forms
  • Inhaler
  • Pill
  • Chewable tablet
  • Granule
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
799 reviews so far
66%
saidit'sworth it
48%
saiditworked well
11%
saidit'sa big hassle

Have you used Advair (fluticasone / salmeterol)?

Leave a review
557 reviews so far
66%
saidit'sworth it
47%
saiditworked well
14%
saidit'sa big hassle

Have you used Singulair (montelukast)?

Leave a review
Side effects
15possible side effects
  • Lung infection
    27%
  • Sore throat
    13%
  • Headaches
    12%
  • Lung inflammation
    7%
  • Hoarseness
    5%
  • Sinus inflammation
    4%
  • Colds and flu
    4%
  • Nausea and vomiting
    4%
  • Stomach upset
    4%
  • Diarrhea
    4%
  • Muscle and joint pain
    4%
  • Stomach flu
    3%
  • Fungal infections
    3%
  • Cough
    3%
  • Bronchitis
    2%
See more detailed side effects
13possible side effects
  • Headache
    18%
  • Flu
    4%
  • Stomach pain
    3%
  • Cough
    3%
  • Lack of energy
    2%
  • Fever
    2%
  • Upset stomach
    2%
  • Dental pain
    2%
  • Stomach infection
    2%
  • Dizziness
    2%
  • Stuffy nose
    2%
  • Rash
    2%
  • Abnormal liver function tests
    2%
See more detailed side effects
Risks and risk factors
  • Increased risk of death
    • Asthma
    • Children under 18
  • Increased risk of infections
    • History of chronic obstructive pulmonary disease (COPD)
    • COPD includes chronic bronchitis and emphysema
    • Age greater than 65 years
  • Mouth and throat infection
    • Not rinsing mouth after use
    • Higher dose of the corticosteroid medication contained in Advair (fluticasone / salmeterol)
  • Asthma attack
  • Heart disease
    • High blood pressure
    • Heart failure
    • Heart beat problems
    • Taking more Advair (fluticasone / salmeterol) than recommended
  • Serious allergic reaction
    • Milk allergy
See more detailed risks and warnings
  • Asthma attacks
    • Exercise-induced asthma
    • Other environmental triggers
  • Aggression and agitation
  • Blood disorder
    • Recent treatment with corticosteroid medicine
    • Lowering dose of corticosteroid medicine
  • Phenylketonuria
    • Phenylketonuria (PKU)
See more detailed risks and warnings