Compare Allegra vs. Flonase

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Allegra (fexofenadine)


Flonase (fluticasone)

Prescription or OTC
Treats allergy symptoms.

Allegra (fexofenadine) relieves allergy symptoms without making you feel drowsy.

3.9/ 5 average rating with 24 reviewsforAllegra
Relieves nasal allergy symptoms.

Flonase (fluticasone) is a good first-choice treatment for allergies of the nose, but long-term use can increase the risk of nosebleeds.

3.7/ 5 average rating with 890 reviewsforFlonase
  • Allegra (fexofenadine) is effective at reducing symptoms for seasonal allergies and chronic hives without significant drowsiness, unlike Benadryl.
  • Approved for kids aged 6 months or older.
  • Allegra (fexofenadine) comes in many forms, like tablet, liquid, and quick-dissolving tablet.
  • Only need to use Flonase (fluticasone) once a day. Its effects can last for up to 24 hours.
  • Available over-the-counter and cheaper than many of its alternatives.
  • Highly effective treatment of allergy symptoms in the nose.
  • Flonase (fluticasone) gives you very little to no side effects since it's a nasal spray and doesn't expose the rest of your body to the medicine.
  • Allegra (fexofenadine)'s effectiveness can wear off over time.
  • The dose needs to be adjusted for people with kidney problems.
  • Flonase (fluticasone) is not an appropriate medicine for people who have an injured nose or had a recent surgery in the nose.
  • Can slow down the growth rate in children.
  • Can increase the risk of bleeding and fungal infections in the nose.
  • Not recommended for those who are also taking other medicines that lower their ability to fight off infections.
Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Liquid
  • Nasal spray
No pricing information available
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24 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

Have you used Allegra (fexofenadine)?

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890 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

Have you used Flonase (fluticasone)?

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Side effects
4possible side effects
  • Dizziness
  • Back Pain
  • Stomach discomfort
  • Pain in hands/feet
See more detailed side effects
7possible side effects
  • Headache
  • Asthma-like symptoms
  • Sore throat
  • Nosebleed
  • Nausea/vomiting
  • Cough
  • Nasal burning/nasal irritation
See more detailed side effects
Risks and risk factors
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Brain damage from too much phenylalanine
    • History of phenylketonuria (PKU)
See more detailed risks and warnings
  • Decreased growth rate in children
    • Children
    • Using the medicine for a long period of time
  • Effect on wound healing
    • People who had recent surgery or injury to the nose
  • Lowered ability to fight off infections
    • People who come into contact with others who have chickenpox, measles, or tuberculosis
    • People who have not received a vaccine for chickenpox, measles, or tuberculosis
  • Damage to nose
    • Using the medicine for a long period of time
  • Sinus infection
    • People who recently had the cold or flu
  • Increased risk of nosebleeds
See more detailed risks and warnings