Compare alosetron vs. Pepto-Bismol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT
Reduces diarrhea in women with severe irritable bowel syndrome (IBS).

Lotronex (alosetron) is good add-on treatment for severe diarrhea in women with IBS, but shouldn't be used in men or those with constipation-dominant IBS.

Relieves heartburn, upset stomach, and diarrhea.

Pepto-Bismol (bismuth subsalicylate) can help for many stomach and intestinal problems, but may take longer to work compared to some other anti-diarrheal medicines.

3.9/ 5 average rating with 1376 reviewsforPepto-Bismol
Upsides
  • Good alternative if nothing else has worked to control your diarrhea.
  • Has fewer side effects than other medicines used to treat diarrhea related to IBS.
  • Pepto-Bismol (bismuth subsalicylate) works well to alleviate stomach and intestinal problems and doesn't have many side effects.
  • Comes in easy to take chewable pills or liquid, if you do not like swallowing pills.
  • Is inexpensive and available over the counter.
  • Coupons are available. Speak to your doctor or pharmacist.
Downsides
  • May be expensive if not covered by your insurance.
  • Only treats diarrhea in women with IBS. Not a good choice if you have constipation related to IBS or are a male with IBS.
  • May not be as strong as other anti-diarrheal or antacid medications.
  • Should not be used for more than 2 days if your diarrhea does not go away or if you have a fever.
  • For symptoms other than diarrhea, should not be used for more than 7 days without your doctor's approval. Speak to your doctor if symptoms persist.
ADVERTISEMENT
Used for
  • Irritable bowel syndrome with severe diarrhea in women
Dosage forms
  • Pill
  • Chewable tablet
  • Liquid
  • Pill
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
Not enough review data.Leave a review
1376 reviews so far
84%
saidit'sworth it
48%
saiditworked well
6%
saidit'sa big hassle

Have you used Pepto-Bismol (bismuth subsalicylate)?

Leave a review
Side effects
4possible side effects
  • Constipation
    16%
  • Stomach pain
    6%
  • Diarrhea
    2%
  • Hemorrhoid bleeding
    2%
See more detailed side effects
The Pepto-Bismol (bismuth subsalicylate) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Serious gastrointestinal problems
    • Daily doses higher than 1 mg
    • Constipation-predominant irritable bowel syndrome
See more detailed risks and warnings
  • Reye's syndrome
    • Children or teenagers that have or are recovering from flu/flu-like symptoms or chickenpox
  • Allergy to salicylates
    • Aspirin allergy
    • NSAID allergy
  • Hearing problems
    • Age 60 or older
  • Drug Interactions
    • Anticoagulants
    • Aspirin-containing medications
See more detailed risks and warnings