Compare Ambien vs. Klonopin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Ambien (zolpidem)

Prescription only

Klonopin (Clonazepam)

Prescription only
Helps you sleep.

Ambien (zolpidem) aids in falling asleep and staying asleep, but it can be habit-forming and might be more likely than other sleep medicines to cause side effects.

3.7/ 5 average rating with 1375 reviewsforAmbien
Controls seizures and helps you relax.

Klonopin (Clonazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety, and to treat seizures. Less severe withdrawal symptoms compared to similar drugs.

3.8/ 5 average rating with 767 reviewsforKlonopin
Upsides
  • Effective at helping people fall asleep faster and sleep longer.
  • Extended release form is particularly good for staying asleep, and you can use it for longer than the immediate release form.
  • Generic is available.
  • Effective at relieving short-term anxiety and sleeplessness.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
  • Can be used alone or with other medicines to treat seizures.
  • Less severe withdrawal symptoms compared to other benzodiazepines.
Downsides
  • Not typically used for long-term treatment because it can be habit-forming.
  • Some people find that Ambien (zolpidem) becomes less effective over time.
  • More likely to cause sleep-walking, sleep-driving, and sleep-eating.
  • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Most people find that it gets less effective over time.
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Used for
Dosage forms
  • Pill
  • Oral spray
  • Sublingual pill
  • Pill
  • Dissolving tablet
Price
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Reviews
1375 reviews so far
67%
saidit'sworth it
50%
saiditworked well
16%
saidit'sa big hassle

Have you used Ambien (zolpidem)?

Leave a review
767 reviews so far
70%
saidit'sworth it
52%
saiditworked well
14%
saidit'sa big hassle

Have you used Klonopin (Clonazepam)?

Leave a review
Side effects
18possible side effects
  • Drowsiness
    8%
  • Headache
    7%
  • Dizziness
    5%
  • Allergic reactions
    4%
  • Sinus infection
    4%
  • Dry mouth
    3%
  • Back pain
    3%
  • Lack of energy
    3%
  • Drugged feeling
    3%
  • Diarrhea
    3%
  • Sore throat
    3%
  • Flu-like symptoms
    2%
  • Racing heart
    2%
  • Lightheadedness
    2%
  • Depression
    2%
  • Abdominal pain
    2%
  • Constipation
    2%
  • Rash
    2%
See more detailed side effects
19possible side effects
  • Somnolence
    37%
  • Dizziness
    8%
  • Upper Respiratory Tract Infection
    8%
  • Depression
    7%
  • Fatigue
    7%
  • Coordination Abnormal
    6%
  • Ataxia
    5%
  • Memory Disturbance
    4%
  • Sinusitis
    4%
  • Influenza
    4%
  • Nervousness
    3%
  • Dysmenorrhea
    3%
  • Dysarthria
    2%
  • Intellectual Ability Reduced
    2%
  • Rhinitis
    2%
  • Coughing
    2%
  • Pharyngitis
    2%
  • Constipation
    2%
  • Allergic Reaction
    2%
See more detailed side effects
Risks and risk factors
  • Dependence and withdrawal
    • Continuous use of Ambien (zolpidem) for 2 weeks or more
  • Driving impairment
    • Alcohol
    • Taking other medications that make you less alert
    • Less than 8 hours of sleep.
  • Abnormal thoughts
    • Undiagnosed psychiatric conditions
  • Performing activities while asleep
    • Taking Ambien (zolpidem) with alcohol or drugs that cause drowsiness
  • Risk of falls and injury
    • Higher dose
    • Liver problems
    • Taking Ambien (zolpidem) with other nervous system depressants
    • Long-term use
    • Elderly (70 years or older)
See more detailed risks and warnings
  • Tolerance and dependence
    • Taking more than the prescribed dose
    • Taking longer than 4 weeks
    • History of drug abuse
  • Withdrawal
    • Long-term use
  • Pregnancy
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
  • Memory problems
See more detailed risks and warnings