Compare Ambien vs. Silenor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Helps you sleep.

Ambien (zolpidem) aids in falling asleep and staying asleep, but it can be habit-forming and might be more likely than other sleep medicines to cause side effects.

3.7/ 5 average rating with 1375 reviewsforAmbien
Helps you relax, and sleep.

Doxepin is a non-addictive way to help people stay asleep, but it comes with a list of side effects.

Upsides
  • Effective at helping people fall asleep faster and sleep longer.
  • Extended release form is particularly good for staying asleep, and you can use it for longer than the immediate release form.
  • Generic is available.
  • In a clinical trial Doxepin was able to significantly improve sleep quality.
  • Doxepin helps improve your appetite, energy level, and sense of well-being, which increases your interests.
  • Once your body gets used to Doxepin, most of the side effects go away.
  • Doxepin comes in a generic form, so it is pretty cheap.
  • Doxepin is not addictive.
Downsides
  • Not typically used for long-term treatment because it can be habit-forming.
  • Some people find that Ambien (zolpidem) becomes less effective over time.
  • More likely to cause sleep-walking, sleep-driving, and sleep-eating.
  • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
  • Some people taking Doxepin walk, drive, eat, and have sex while sleeping. Be sure to tell your doctor if this happens to you.
  • Doxepin can increase your appetite, leading to weight gain.
  • Taking Doxepin can make emptying your bladder difficult.
  • Some people have suicidal thoughts when taking Doxepin.
  • Doxepin can interact with many different medications, vitamins, and alternative treatments.
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Used for
  • Alcoholism - Anxiety - Depression Anxiety - Depression Anxiety - Depression - Psychoneurotic personality disorder Insomnia Pruritus (Moderate)
  • Due to atopic dermatitis or lichen simplex chronicus
  • Urticaria
Dosage forms
  • Pill
  • Oral spray
  • Sublingual pill
  • Pill
  • Liquid
Price
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Reviews
1375 reviews so far
67%
saidit'sworth it
50%
saiditworked well
16%
saidit'sa big hassle

Have you used Ambien (zolpidem)?

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Side effects
18possible side effects
  • Drowsiness
    8%
  • Headache
    7%
  • Dizziness
    5%
  • Allergic reactions
    4%
  • Sinus infection
    4%
  • Dry mouth
    3%
  • Back pain
    3%
  • Lack of energy
    3%
  • Drugged feeling
    3%
  • Diarrhea
    3%
  • Sore throat
    3%
  • Flu-like symptoms
    2%
  • Racing heart
    2%
  • Lightheadedness
    2%
  • Depression
    2%
  • Abdominal pain
    2%
  • Constipation
    2%
  • Rash
    2%
See more detailed side effects
The Silenor (Doxepin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Dependence and withdrawal
    • Continuous use of Ambien (zolpidem) for 2 weeks or more
  • Driving impairment
    • Alcohol
    • Taking other medications that make you less alert
    • Less than 8 hours of sleep.
  • Abnormal thoughts
    • Undiagnosed psychiatric conditions
  • Performing activities while asleep
    • Taking Ambien (zolpidem) with alcohol or drugs that cause drowsiness
  • Risk of falls and injury
    • Higher dose
    • Liver problems
    • Taking Ambien (zolpidem) with other nervous system depressants
    • Long-term use
    • Elderly (70 years or older)
See more detailed risks and warnings
No information currently available