Compare Amerge vs. Cafergot
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats migraine headaches.
Amerge (naratriptan) isn't as good as other similar medications for migraines, but can be good if other drugs haven't worked for you.
Treats migraine headaches.
Cafergot (ergotamine / caffeine) can treat migraines, but you're more likely to have side effects.
- Amerge (naratriptan) is a good alternative to other triptans since it's less likely to cause side effects and if other triptans haven't worked for you.
- Available as a generic, which makes it cheaper than other medicines and is more likely to be covered by insurances.
- Amerge (naratriptan) comes in two different strengths.
- Cafergot (ergotamine / caffeine) works better than other medicines if your migraines usually last more than 2 days or if you have more frequent migraines.
- Amerge (naratriptan) is only available as a pill that must be swallowed, so it might not be good if you have trouble swallowing when you have a migraine.
- Unlike other migraine medications, you have to wait for 4 hours before you can take the second dose of Amerge (naratriptan).
- Amerge (naratriptan) is not as good as other medications for treating nausea that can happen with migraines.
- Cafergot (ergotamine / caffeine) can't stop migraines from happening. They can only treat them.
- Cafergot (ergotamine / caffeine) can only be used for migraines. It doesn't work for other types of headaches.
- Smoking or using products that contain nicotine can make Cafergot (ergotamine / caffeine) less effective.
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6possible side effects
- Stomach problems6%
- Nervous system issues4%
- Unusual sensation2%
- Fatigue or uneasiness2%
- Pain and pressure sensation2%
The Cafergot (ergotamine / caffeine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Heart attack
- Heart disease
- history of chest pain/angina
- uncontrolled high blood pressure
- History of a stroke
- Medication overuse headache
- Using Amerge (naratriptan) for more than 10 days a month
- Serotonin syndrome
- Tricyclic antidepressants
- ADHD medicines
- Increased blood pressure
- Uncontrolled high blood pressure
- Blood vessel issues
- High blood pressure
- history of stroke
- History of clots in the legs or arms (DVT)
- Heart and circulation problems
- Overdosing Cafergot (ergotamine / caffeine)
- Taking triptans (Imitrex, Axert, Maxalt, Amerge, Frova) for migraines
- Dependency and withdrawal
- Taking Cafergot (ergotamine / caffeine) regularly for months
- Danger to fetus