Compare amoxicillin vs. ampicillin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT

Amoxil (amoxicillin)

Prescription only

ampicillin

Prescription only
Treats bacterial infections.

Amoxil (amoxicillin) is a good and cheap antibiotic that comes in different forms to treat many types of bacterial infections.

3.7/ 5 average rating with 786 reviewsforamoxicillin
Treats bacterial infections.

ampicillin is a cheap antibiotic good for treating many types of bacterial infections, but many bacteria are resistant to it.

Upsides
  • First choice medicine to treat many bacterial infections.
  • Available in generic.
  • Available in different forms: tablet, capsule, and liquid. The liquid comes in many different flavors to make it taste better for people who don't like pills.
  • Side effects are generally not too bad compared to other antibiotics.
  • Treats many types of bacterial infections and has generally few side effects.
  • Available in generic.
  • If you have trouble swallowing pills, ampicillin is available as a capsule and liquid.
Downsides
  • While Amoxil (amoxicillin) can be used to treat different bacterial infections, many don't respond to it.
  • Can cause diarrhea, nausea, and vomiting.
  • Except for the extended-release form, you have to take Amoxil (amoxicillin) 2 to 3 times a day, which can be hard to remember.
  • The extended-release form can be more expensive because it's a brand name.
  • You usually have to take ampicillin at least four times a day to treat your infection, which is more frequent than some other antibiotics.
  • ampicillin has to be taken on an empty stomach to increase absorption, which can cause stomach upset.
ADVERTISEMENT
Used for
Dosage forms
  • Pill
  • Chewable tablet
  • Extended-release tablet
  • Liquid
  • Pill
  • Liquid
  • Injection
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
786 reviews so far
62%
saidit'sworth it
45%
saiditworked well
14%
saidit'sa big hassle

Have you used Amoxil (amoxicillin)?

Leave a review
Not enough review data.Leave a review
Side effects
The Amoxil (amoxicillin) FDA package insert doesn’t have numbers about how common side effects are.
The ampicillin FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Interaction with birth control
    • Using oral birth control pills
  • Severe diarrhea
    • Taking Amoxil (amoxicillin) for a long time
  • Severe allergic reaction
    • History of penicillin allergies
  • New infections while taking Amoxil (amoxicillin)
    • Weakened immune system
    • Not taking Amoxil (amoxicillin) correctly
  • Rash
    • Mononucleosis
See more detailed risks and warnings
  • C. difficile diarrhea
    • Taking ampicillin for a long time
  • Severe allergic reaction
    • History of penicillin allergies
  • Decreased effectiveness of birth control pills
    • Taking birth control pills
  • Rash
    • Children
    • Mononucleosis
See more detailed risks and warnings