Compare Anafranil vs. maprotiline
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Helps control obsessive or compulsive behaviors.
Anafranil (clomipramine) effectively treats obsessive-compulsive disorder (OCD), but has potentially intolerable side effects.
Stabilizes your mood.
While Ludiomil (maprotiline) is part of the first choice of medicines to treat depression, it can cause drowsiness and dehydration.
Upsides
- Anafranil (clomipramine) can help with falling sleep.
- Anafranil (clomipramine) has a lower risk of causing heart problems compared to other medications like it.
- Safe to use by children.
- Ludiomil (maprotiline) is available in generic.
- Ludiomil (maprotiline) doesn't cause sleep problems, unlike other medicines used to treat depression.
Downsides
- Anafranil (clomipramine) is more likely to cause side effects than other medications for OCD.
- Anafranil (clomipramine) can affect sexual performance for men.
- It is not recommended for the elderly because it can cause fainting and falls.
- Ludiomil (maprotiline) can make you very drowsy compared to other similar medicines.
- Ludiomil (maprotiline) can cause weight gain, fainting, and make you feel dehydrated.
- Stopping Ludiomil (maprotiline) suddenly without telling your doctor can be dangerous.
- You might not notice changes in your mood until you've taken Ludiomil (maprotiline) for several weeks.
Used for
- Bipolar disorder
- Depression
- Dysthymia
- Mixed anxiety and depressive disorder
- Pain
Dosage forms
- Pill
- Pill
Price
Lowest price
$20.90
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Side effects
109possible side effects
- Dry mouth84%
- Sleepiness54%
- Tremor54%
- Dizziness54%
- Headache52%
- Constipation47%
- Ejaculation failure42%
- Fatigue39%
- Nausea33%
- Increased sweating28%
- Insomnia25%
- Upset stomach22%
- Loss of appetite22%
- Sex drive changes21%
- Impotence20%
- Nervousness18%
- Weight increase18%
- Abnormal vision18%
- Sore throat14%
- Urinary problems14%
- Muscle contractions13%
- Diarrhea13%
- Joint pain13%
- Abdominal pain13%
- Runny nose12%
- Menstrual cramps12%
- Increased appetite11%
- Burning/prickling skin sensation9%
- Memory problems9%
- Anxiety9%
- Sleep disorder9%
- Rash8%
- Flushing8%
- Changes in taste8%
- Twitching7%
- Vomiting7%
- Memory impairment7%
- Chest pain7%
- Allergy7%
- Weight decrease7%
- Asthma attacks7%
- Urinary retention7%
- Itching of the skin6%
- Gas6%
- Changes in blood pressure6%
- Stuffy nose6%
- Coughing6%
- Urinary tract infection6%
- Ringing in the ears6%
- Back pain6%
- Impaired concentration5%
- Depression5%
- Tooth disorder5%
- Hot flushes5%
- Increased urination5%
- Increased muscle tone4%
- Fever4%
- Palpitation4%
- Fast heartbeat4%
- Unusual milk production4%
- Menstrual disorder4%
- Pain4%
- Ear infections4%
- Changes in heartbeat4%
- Psychosomatic disorder3%
- Yawning3%
- Confusion3%
- Speech disorder3%
- Abnormal dreaming3%
- Agitation3%
- Migraine3%
- Excess tearing3%
- Social detachment2%
- Irritability2%
- Mood swings2%
- Skin irritation2%
- Acne2%
- Dry skin2%
- Gastrointestinal disorder2%
- Difficulty swallowing2%
- Local swelling2%
- Chills2%
- Nose bleed2%
- Painful urination2%
- Bladder pain2%
- Vaginal itching2%
- Increased vaginal discharge2%
- Breast enlargement2%
- Pupil dilation2%
- Thirst2%
- Muscle twitching2%
- Tingling or burning sensation2%
- Hypertonia2%
- Panic reaction2%
- Aggressive reaction2%
- Muscle weakness2%
- Abnormal skin odor2%
- Excessive burping2%
- Sores around the mouth2%
- Lack of energy2%
- Bad breath2%
- Fainting2%
- Dyspnea2%
- Laryngitis2%
- Changes in pupils2%
- Eyelid twitching2%
- Eye allergies2%
- Balance problems2%
- Anemia2%
12possible side effects
- Dry mouth22%
- Drowsiness16%
- Dizziness8%
- Constipation6%
- Nervousness6%
- Weakness & fatigue4%
- Headache4%
- Vision changes4%
- Anxiety3%
- Difficulty controlling movements3%
- Trouble sleeping2%
- Nausea2%
Risks and risk factors
- Suicidal thoughts or behavior
- Age 24 years or younger
- Serotonin syndrome
- Antidepressants
- Lithium
- Triptans
- St. John's wort
- Fentanyl
- Tramadol
- MAO inhibitors
- Seizures
- History of seizure
- Taking other medicines that increase seizure risk
- Brain damage
- Alcoholism
- Withdrawal symptoms
- Stopping Anafranil (clomipramine) suddenly
- Low blood pressure
- Age 65 years or older
- Eye problems
- Higher risk of suicide
- People under age 24
- Possible bipolar disorder
- Heart problems
- History of heart attack or heart disease
- Higher risk of infections