Compare Androgel vs. Axiron

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats low testosterone.

Androgel (testosterone) is a convenient topical form of testosterone hormone replacement for males, but you should be careful that the gel doesn't rub off on others.

Treats low testosterone.

This testosterone topical solution is a convenient topical form of hormone replacement that's less likely to rub off on other people you come into contact with, but it's not available as a generic yet.

Upsides
  • Androgel (testosterone) is an effective medication for treating low testosterone levels.
  • You put it on like a lotion, so it's very easy to apply.
  • It is available as a cheaper, generic form.
  • Androgel (testosterone) does not need to be dose adjusted if you have liver or kidney problems.
  • You're less likely with this formulation to transfer testosterone topical solution to another person since this is applied to the armpits -- unlike some other forms of topical testosterone.
  • You can use your regular deodorant or antiperspirant, but just make sure to apply that first before using testosterone topical solution.
Downsides
  • You have to make sure that you cover the area where you place Androgel (testosterone) after it's dry, otherwise it can rub off on people.
  • You have to wait at least 2 hours before you shower or swim after putting on Androgel (testosterone), otherwise your body won't absorb the entire amount.
  • Only available as brand name.
  • You have to wait at least 2 hours after applying testosterone topical solution before you can swim or bathe, otherwise your body won't absorb the entire amount.
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Used for
  • Metastatic breast cancer
  • Delayed puberty
  • Hypogonadism
  • Low testosterone
  • Male osteoporosis
  • Weight gain
Dosage forms
  • Gel
  • Topical
Price
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Reviews
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Side effects
5possible side effects
  • Increased PSA levels
    11%
  • Emotional lability
    3%
  • High blood pressure
    2%
  • Increased hematocrit or hemoglobin
    2%
  • Skin reactions
    2%
See more detailed side effects
7possible side effects
  • Application Site Irritation
    8%
  • Application Site Erythema
    7%
  • Hematocrit Increased
    7%
  • Headache
    6%
  • Diarrhea
    4%
  • Vomiting
    4%
  • PSA Increased
    4%
See more detailed side effects
Risks and risk factors
  • Exposing others to Androgel (testosterone)
  • Blood clots
  • Swelling in the legs
    • Heart disease
    • Liver disease
    • Kidney disease
  • Elevated red blood cell count
  • High calcium in the blood
    • History of cancer
  • Flammability
    • Smoking
    • Exposure to fire or flames
See more detailed risks and warnings
No information currently available