Compare Angeliq vs. Climara Pro
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Relieves hot flashes and vaginal dryness due to menopause.
Angeliq (drospirenone / estradiol) helps relieve menopausal symptoms. There can be many side effects, so it's important to think through the benefits and potential hassles of this drug before using it.
Relieves hot flashes and lowers your risk of osteoporosis.
The Climara Pro (estradiol / levonorgestrel patch) is effective at treating menopause symptoms, and it can be a good choice for women who need estrogen/progestin combination medications but prefer to use a patch once a week instead of pills every day.
Upsides
- Angeliq (drospirenone / estradiol) replaces estrogen to your whole body and relieves multiple symptoms due to low estrogen (hot flashes, night sweats, vaginal dryness).
- Useful for women who experience moderate to severe symptoms of menopause.
- Improves mood, energy, and mental alertness for some people.
- Good for women with an intact uterus. The drospirenone (a progestin) protects against the risk of cancer in the uterus from estrogen treatment.
- Once-a-week patch. Good for people who don't want to take daily pills.
- Replaces estrogen in your body and relieves multiple symptoms from low estrogen, such as hot flashes and vaginal dryness.
- Fewer side effects than pills since patches contain lower amounts of hormones.
- Good for women with an intact uterus. The progestin in the patch protects against the risk of cancer in the uterus.
- The Climara Pro (estradiol / levonorgestrel patch) patch has a lower risk of causing blood clots and stroke compared to other forms containing the same medicines.
Downsides
- There are more possible side effects since it exposes your whole body to two hormones.
- Angeliq (drospirenone / estradiol) can't be used by women who have had their uterus removed.
- You may get irregular bleeding and spotting that can last a few months to a year.
- Compared to other estrogen-progestin combination medicines, you might be more likely to have blood clots with Angeliq (drospirenone / estradiol).
- Angeliq (drospirenone / estradiol) might increase your potassium, which can be dangerous if you're taking other medicines that do the same.
- More potential side effects than medications with one ingredient since Climara Pro (estradiol / levonorgestrel patch) exposes your whole body to two hormones.
- Increases your risk of developing blood clots and stroke.
- You may get irregular bleeding and spotting that can last a few months to a year.
- The patch can fall off, especially if you like to regularly swim, take baths, or use saunas.
- Can be expensive since it's only available as a brand name product.
Used for
- Hot flashes
- Menopause
- Hot flashes and night sweats
- Prevention of postmenopausal osteoporosis
Dosage forms
- Pill
- Patch
Price
Lowest price
$194.88
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$241.37
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Side effects
7possible side effects
- Stomach pain6%
- Headache6%
- Yeast infections6%
- Breast pain3%
- Nausea3%
- Diarrhea2%
- Swelling of arms and legs2%
22possible side effects
- Skin irritation41%
- Vaginal bleeding37%
- Breast pain19%
- Lung infection13%
- Back pain6%
- Depression6%
- Flu like symptoms5%
- Pain5%
- Headache5%
- Stomach pain4%
- Gas4%
- Swelling of arms and legs4%
- Joint pain4%
- Airway inflammation4%
- Sinus infection4%
- Accidental injury3%
- Infection3%
- High blood pressure3%
- Weight gain3%
- Bladder infection3%
- Rash2%
- Vaginal inflammation2%
Risks and risk factors
- Endometrial cancer
- Using estrogen for more than one year
- Breast cancer
- Personal or family history of breast cancer
- Using estrogen for more than one year
- Increased risk of blood clots and stroke
- Personal or family history of blood clots
- Smoking
- Obesity
- Systemic lupus erythematosus (SLE)
- Increased risk of heart disease
- Smoking
- Obesity
- High blood pressure
- High blood sugar
- High cholesterol
- Age 50 or older
- Dementia
- Age 65 or older
- Increased potassium
- Kidney disease
- Liver disease
- Addison's disease
- Medicines that cause high potassium levels
- Endometrial cancer
- Using estrogen for more than one year
- Breast cancer
- Personal or family history of breast cancer
- Using estrogen for more than one year
- Increased risk of blood clots and stroke
- Personal or family history of blood clots
- Smoking
- Obesity
- Systemic lupus erythematosus (SLE)
- Dementia
- Age 65 or older
- Pancreas swelling (pancreatitis)
- High levels of triglycerides