Compare Antara vs. simvastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Antara (fenofibrate)

Prescription only

Zocor (simvastatin)

Prescription only
Lowers cholesterol and triglycerides.

Antara (fenofibrate) is effective at lowering triglyceride and cholesterol levels, but may cause liver problems and muscle pain.

2.5/ 5 average rating with 56 reviewsforAntara
Lowers cholesterol.

Zocor (simvastatin) is a good medication to improve your cholesterol.

3.8/ 5 average rating with 1176 reviewsforsimvastatin
Upsides
  • Antara (fenofibrate) can reduce triglycerides by about 20-50%.
  • Although not as effective at lowering triglycerides, Antara (fenofibrate) can lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
  • There is a less expensive generic version available.
  • You only need to take it once a day, with or without food.
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Available in generic.
  • Available in combination pills with other cholesterol medicines.
Downsides
  • Not as effective as statins in lowering cholesterol levels. You shouldn't take Antara (fenofibrate) by itself to lower cholesterol.
  • Drinking large amounts of alcohol regularly while taking Antara (fenofibrate) can increase your risk of liver damage.
  • Tell your doctor if you have a history of gallbladder, liver or kidney disease. Antara (fenofibrate) might not be the best choice to lower your triglyceride levels.
  • Antara (fenofibrate) can interact with other medications such as warfarin, colchicine, and sulfonylureas.
  • Antara (fenofibrate) was not shown to reduce rates of death in people with type 2 diabetes.
  • You are at higher risk for side effects if you are female, are 65 years or older, drink alcohol every day, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
  • Can have more drug interactions than some other drugs in the same class (statins).
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Used for
Dosage forms
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Price
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Reviews
56 reviews so far
27%
saidit'sworth it
14%
saiditworked well
29%
saidit'sa big hassle

Have you used Antara (fenofibrate)?

Leave a review
1176 reviews so far
61%
saidit'sworth it
48%
saiditworked well
14%
saidit'sa big hassle

Have you used Zocor (simvastatin)?

Leave a review
Side effects
11possible side effects
  • Abnormal liver function tests
    8%
  • Respiratory disorder
    6%
  • Stomach pain
    5%
  • Back pain
    3%
  • Headache
    3%
  • Increased AST
    3%
  • Increased ALT
    3%
  • Increased creatine phosphokinase
    3%
  • Nausea
    2%
  • Constipation
    2%
  • Hay fever
    2%
See more detailed side effects
14possible side effects
  • Bronchitis
    7%
  • Abdominal pain
    6%
  • Atrial fibrillation
    6%
  • Stomach problems
    5%
  • Balance problems
    5%
  • Eczema
    5%
  • Diabetes
    4%
  • Muscle pain
    4%
  • Insomnia
    4%
  • Edema/swelling
    3%
  • Headache
    3%
  • Infection, urinary tract
    3%
  • Constipation
    2%
  • Sinus infection
    2%
See more detailed side effects
Risks and risk factors
  • Muscle pain
    • Taking Antara (fenofibrate) with statins
    • Elderly patients
    • Patients with diabetes
    • Patients with a history of renal failure.
  • Liver damage
    • History of liver disease
  • Gallstones
    • History of gallstones
  • Increased bleeding risk
    • Taking Antara (fenofibrate) with anticoagulants
  • Inflammation of pancreas
  • Changes in blood tests
See more detailed risks and warnings
  • Muscle pain and kidney damage
    • Kidney disease
    • High dose of Zocor (simvastatin)
    • Combining Zocor (simvastatin) with other cholesterol-lowering drugs
    • Older age
    • Female gender
  • Liver damage
    • Heavy alcohol use
    • History of chronic liver disease
  • Harm to unborn baby
    • Pregnancy
    • Breast feeding
  • Drug interactions
    • Certain drugs can increase the dose of Zocor (simvastatin) in the body
  • High blood sugar
    • History of high blood sugar
See more detailed risks and warnings