Compare Antara vs. simvastatin
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers cholesterol and triglycerides.
Antara (fenofibrate) is effective at lowering triglyceride and cholesterol levels, but may cause liver problems and muscle pain.
2.5/ 5 average rating with 56 reviewsforAntara
Zocor (simvastatin) is a good medication to improve your cholesterol.
3.8/ 5 average rating with 1176 reviewsforsimvastatin
- Antara (fenofibrate) can reduce triglycerides by about 20-50%.
- Although not as effective at lowering triglycerides, Antara (fenofibrate) can lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
- There is a less expensive generic version available.
- You only need to take it once a day, with or without food.
- Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
- Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
- Available in generic.
- Available in combination pills with other cholesterol medicines.
- Not as effective as statins in lowering cholesterol levels. You shouldn't take Antara (fenofibrate) by itself to lower cholesterol.
- Drinking large amounts of alcohol regularly while taking Antara (fenofibrate) can increase your risk of liver damage.
- Tell your doctor if you have a history of gallbladder, liver or kidney disease. Antara (fenofibrate) might not be the best choice to lower your triglyceride levels.
- Antara (fenofibrate) can interact with other medications such as warfarin, colchicine, and sulfonylureas.
- Antara (fenofibrate) was not shown to reduce rates of death in people with type 2 diabetes.
- You are at higher risk for side effects if you are female, are 65 years or older, drink alcohol every day, or have liver disease, kidney disease, or diabetes.
- Not safe to use if you're pregnant.
- Can have more drug interactions than some other drugs in the same class (statins).
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56 reviews so far
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11possible side effects
- Abnormal liver function tests8%
- Respiratory disorder6%
- Stomach pain5%
- Back pain3%
- Increased AST3%
- Increased ALT3%
- Increased creatine phosphokinase3%
- Hay fever2%
14possible side effects
- Abdominal pain6%
- Atrial fibrillation6%
- Stomach problems5%
- Balance problems5%
- Muscle pain4%
- Infection, urinary tract3%
- Sinus infection2%
Risks and risk factors
- Muscle pain
- Taking Antara (fenofibrate) with statins
- Elderly patients
- Patients with diabetes
- Patients with a history of renal failure.
- Liver damage
- History of liver disease
- History of gallstones
- Increased bleeding risk
- Taking Antara (fenofibrate) with anticoagulants
- Inflammation of pancreas
- Changes in blood tests
- Muscle pain and kidney damage
- Kidney disease
- High dose of Zocor (simvastatin)
- Combining Zocor (simvastatin) with other cholesterol-lowering drugs
- Older age
- Female gender
- Liver damage
- Heavy alcohol use
- History of chronic liver disease
- Harm to unborn baby
- Breast feeding
- Drug interactions
- Certain drugs can increase the dose of Zocor (simvastatin) in the body
- High blood sugar
- History of high blood sugar