Compare Apriso vs. Colazal

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Maintains remission of ulcerative colitis

Apriso (mesalamine) is an effective medication for maintaining remission of ulcerative colitis that's generally well tolerated, but commonly causes headache.

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  • Apriso (mesalamine) is only available as a tablet, however, mesalamine is available in different forms, including tablets, capsules, enemas, and suppositories.
  • Certain forms of Apriso (mesalamine) can be used during pregnancy. Talk to your doctor if you're pregnant, or plan on becoming pregnant, and you have bowel inflammation.
  • It is a good option even if you have kidney or liver disease.
  • Since Apriso (mesalamine) is an extended release form, the pill is taken only once a day compared to other similar medicines and can be less irritating to the stomach and intestines.
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  • Although you only have to take it once in the morning, you may need to take 4 capsules.
  • Apriso (mesalamine) is not available as a cheaper, generic form.
  • Should only be used if you're 18 or older.
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Used for
  • Ulcerative colitis (Mild to Moderate)
  • Active
  • Ulcerative colitis
  • Remission maintenance
Dosage forms
  • Extended-release pill
  • Pill
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Side effects
7possible side effects
  • Headache
  • Diarrhea
  • Upper stomach pain
  • Nausea
  • Common cold
  • Flu-like symptoms
  • Sinus infection
See more detailed side effects
The Colazal (Balsalazide) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Liver problems
    • Preexisting liver problems
    • Taking other medications toxic to the liver
  • Kidney problems
    • Preexisting kidney problems
    • Taking medications toxic to the kidney
  • Build up of phenylalanine in the body
    • Phenylketonuria (PKU)
  • Serious allergic reactions
    • Sulfasalazine reaction
  • Acute intolerance syndrome
See more detailed risks and warnings
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