Compare Apriso vs. Delzicol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Apriso (mesalamine)

Prescription only

Delzicol (mesalamine)

Prescription only
Maintains remission of ulcerative colitis

Apriso (mesalamine) is an effective medication for maintaining remission of ulcerative colitis that's generally well tolerated, but commonly causes headache.

Treats ulcerative colitis and helps prevent flares.

Delzicol (mesalamine) effectively reduces symptoms of a flare for mild to moderate ulcerative colitis in both children and adults, but can cause burping and stomach discomfort.

Upsides
  • Apriso (mesalamine) is only available as a tablet, however, mesalamine is available in different forms, including tablets, capsules, enemas, and suppositories.
  • Certain forms of Apriso (mesalamine) can be used during pregnancy. Talk to your doctor if you're pregnant, or plan on becoming pregnant, and you have bowel inflammation.
  • It is a good option even if you have kidney or liver disease.
  • Since Apriso (mesalamine) is an extended release form, the pill is taken only once a day compared to other similar medicines and can be less irritating to the stomach and intestines.
  • Delzicol (mesalamine) effectively treats ulcerative colitis flares.
  • This drug is often used as the first-choice treatment in adults and children.
  • If you have trouble swallowing the drug whole, the pill can be opened and you can swallow the tablets inside.
  • Can be used in children 5 years and older.
Downsides
  • Although you only have to take it once in the morning, you may need to take 4 capsules.
  • Apriso (mesalamine) is not available as a cheaper, generic form.
  • Should only be used if you're 18 or older.
  • Treatment dosage must be taken 3 times a day for a total of 6 weeks.
  • Can take a few weeks before you start to feel the effects.
  • Delzicol (mesalamine) is not available as a cheaper, generic form.
  • Combination therapy with oral and rectal forms may be needed for some people.
  • This form of mesalamine isn't used for maintenance, only to help reduce flare symptoms.
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Used for
Dosage forms
  • Extended-release pill
  • Delayed-release pill
Price
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Reviews
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Side effects
7possible side effects
  • Headache
    11%
  • Diarrhea
    8%
  • Upper stomach pain
    5%
  • Nausea
    4%
  • Common cold
    4%
  • Flu-like symptoms
    4%
  • Sinus infection
    3%
See more detailed side effects
9possible side effects
  • Burping
    26%
  • Abdominal pain
    21%
  • Constipation
    11%
  • Dizziness
    9%
  • Runny nose
    8%
  • Back pain
    6%
  • Rash
    6%
  • Upset stomach
    4%
  • Flu syndrome
    4%
See more detailed side effects
Risks and risk factors
  • Liver problems
    • Preexisting liver problems
    • Taking other medications toxic to the liver
  • Kidney problems
    • Preexisting kidney problems
    • Taking medications toxic to the kidney
  • Build up of phenylalanine in the body
    • Phenylketonuria (PKU)
  • Serious allergic reactions
    • Sulfasalazine reaction
  • Acute intolerance syndrome
See more detailed risks and warnings
  • Kidney problems
    • Preexisting kidney problems
    • Taking medications toxic to the kidney
  • Liver problems
    • Preexisting liver problems
    • Taking other medications toxic to the liver
  • Serious allergic reactions
    • Sulfasalazine reaction
  • Abnormal response to Delzicol (mesalamine)
See more detailed risks and warnings