Compare Arimidex vs. Aromasin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Arimidex (anastrozole)

Prescription only

Aromasin (exemestane)

Prescription only
Treats breast cancer in postmenopausal women

Arimidex (anastrozole) is one of the first-line treatments for breast cancer that helps improve survival rates, but it is used only in post-menopausal women.

Treats breast cancer in postmenopausal women.

Aromasin (exemestane) treats advanced breast cancer in post-menopausal women and helps lower their chances of the cancer coming back or spreading to the other breast. However, the overall survival rates for women who take Aromasin (exemestane) is the same as another treatment option, specifically Novaldex.

Upsides
  • Available as a pill unlike some chemotherapies.
  • Can be used safely and effectively even in those with kidney or liver problems.
  • Available as a generic version
  • Can be used as first line or second line hormone therapy for certain advanced breast cancers.
  • Unlike other chemotherapies, Aromasin (exemestane) comes as a pill.
  • Can be used safely and effectively by those with kidney or liver problems.
  • It is available as a generic pill.
  • Financial assistance is available if you have trouble affording this medication.
  • Aromasin (exemestane) works a little differently from other hormone therapies. If you are having difficulty with other hormone therapies, your doctor may suggest Aromasin (exemestane).
Downsides
  • Arimidex (anastrozole) can cause serious allergic reactions, such as rash, hives, tightness in the chest or throat, and trouble breathing.
  • You will have to get your blood drawn regularly while on Arimidex (anastrozole).
  • Unlike other chemotherapies, Arimidex (anastrozole) reduces the amount of estrogen in your body, which can lead to weaker bones and other symptoms typically only seen in postmenopausal women.
  • Aromasin (exemestane) can cause serious allergic reactions.
  • Some people may not be able to tolerate the bone pain and body aches from Aromasin (exemestane).
  • Aromasin (exemestane) reduces the amount of estrogen in your body which can lead to weaker bones and other symptoms typically only seen in postmenopausal women.
  • Although Aromasin (exemestane) is available as a generic, it can be more expensive than similar hormone therapies.
  • Aromasin (exemestane) is only approved for use after tamoxifen therapy.
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Used for
  • Hormone receptor positive breast cancer
  • Reduction of risk for breast cancer
  • Hormone receptor positive breast cancer
  • Reduction of risk for breast cancer
Dosage forms
  • Pill
  • Pill
Price
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Reviews
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Side effects
26possible side effects
  • Stomach pain
    32%
  • Dilation of blood vessels
    31%
  • Hot flashes
    24%
  • Fatigue
    19%
  • Mood disorder
    19%
  • Worsening of heart disease in those with pre-existing heart condition
    17%
  • Joint inflammation
    17%
  • Nausea
    16%
  • Weakness
    16%
  • Headache
    14%
  • Pain
    14%
  • Severe chest pain in those with pre-existing heart condition
    12%
  • Vomiting
    11%
  • Weak bones
    11%
  • Back pain
    11%
  • Inflammation of the throat
    10%
  • Difficulty breathing
    10%
  • Swelling
    9%
  • Skin rash
    9%
  • Joint pain
    9%
  • Bone pain
    9%
  • Coughing
    9%
  • High blood pressure
    8%
  • Depression
    8%
  • Heart disease
    4%
  • Severe chest pain
    2%
See more detailed side effects
13possible side effects
  • Hot flashes
    21%
  • Fatigue
    16%
  • Joint pain
    15%
  • Headache
    13%
  • Difficulty sleeping
    12%
  • Increased sweating
    12%
  • Dizziness
    10%
  • High blood pressure
    10%
  • Nausea
    9%
  • Pain in limbs
    9%
  • Back pain
    9%
  • Depression
    6%
  • Vision changes
    5%
See more detailed side effects
Risks and risk factors
  • Decreased bone mineral density
  • High cholesterol
    • High cholesterol
  • Heart disease
    • History of heart problems
See more detailed risks and warnings
  • Decreased bone density
  • Lab abnormalities
  • Drug-drug interactions
  • Embryo-fetal toxicity
    • Pregnant females
See more detailed risks and warnings