Compare Aromasin vs. Femara

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats breast cancer in postmenopausal women.

Aromasin (exemestane) treats advanced breast cancer in post-menopausal women and helps lower their chances of the cancer coming back or spreading to the other breast. However, the overall survival rates for women who take Aromasin (exemestane) is the same as another treatment option, specifically Novaldex.

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Upsides
  • Unlike other chemotherapies, Aromasin (exemestane) comes as a pill.
  • Can be used safely and effectively by those with kidney or liver problems.
  • It is available as a generic pill.
  • Financial assistance is available if you have trouble affording this medication.
  • Aromasin (exemestane) works a little differently from other hormone therapies. If you are having difficulty with other hormone therapies, your doctor may suggest Aromasin (exemestane).
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Downsides
  • Aromasin (exemestane) can cause serious allergic reactions.
  • Some people may not be able to tolerate the bone pain and body aches from Aromasin (exemestane).
  • Aromasin (exemestane) reduces the amount of estrogen in your body which can lead to weaker bones and other symptoms typically only seen in postmenopausal women.
  • Although Aromasin (exemestane) is available as a generic, it can be more expensive than similar hormone therapies.
  • Aromasin (exemestane) is only approved for use after tamoxifen therapy.
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Used for
  • Hormone receptor positive breast cancer
  • Reduction of risk for breast cancer
  • Breast cancer
  • Adjuvant
  • Postmenopausal
  • Hormone receptor-positive Breast cancer
  • Advanced
  • Postmenopausal
  • Following antiestrogen therapy Breast cancer
  • Extended adjuvant
  • Postmenopausal
  • Following 5 years of tamoxifen therapy Breast cancer
  • Locally advanced or metastatic
  • Postmenopausal
  • Hormone receptor-positive or unknown
  • First-line
  • Breast cancer
  • Neoadjuvant
  • Postmenopausal
  • Hormone receptor-positive Delayed puberty Endometriosis - Ovulation induction Ovulation induction - Polycystic ovary syndrome
Dosage forms
  • Pill
  • Pill
Price
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Reviews
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Side effects
13possible side effects
  • Hot flashes
    21%
  • Fatigue
    16%
  • Joint pain
    15%
  • Headache
    13%
  • Difficulty sleeping
    12%
  • Increased sweating
    12%
  • Dizziness
    10%
  • High blood pressure
    10%
  • Nausea
    9%
  • Pain in limbs
    9%
  • Back pain
    9%
  • Depression
    6%
  • Vision changes
    5%
See more detailed side effects
The Femara (Letrozole) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Decreased bone density
  • Lab abnormalities
  • Drug-drug interactions
  • Embryo-fetal toxicity
    • Pregnant females
See more detailed risks and warnings
No information currently available