Compare Artane vs. Azilect
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats Parkinson's disease.
Artane (trihexyphenidyl) can be used to control tremors if you have Parkinson's, but it can really dry you out and cause other side effects.
Treats Parkinson's disease.
Azilect (rasagiline) is one of the recommended medicines to treat Parkinson's disease. It is now available in generic, which makes it more affordable for people without insurance.
Upsides
- Artane (trihexyphenidyl) can be used with other medicines and in people with advanced Parkinson's who still have tremors.
- Effective by itself for people under 70 with Parkinson's who only have problems with tremors.
- Less severe side effects compared to other medicines for tremors.
- Available as generic.
- Azilect (rasagiline) is one of the go-to medicines for Parkinson's disease. It can be used in early and late stages of the disease.
- Taking Azilect (rasagiline) by itself can help slow down Parkinson's disease, but it works better when it's given with other medicines.
- Azilect (rasagiline) is available as generic as well as brand name, so there are usually lower out-of-pocket costs for you with insurance.
Downsides
- Not recommended in people over 65 or in people with memory problems.
- Artane (trihexyphenidyl) only calms down tremors because of Parkinson's, but it doesn't treat other symptoms.
- Can't be used in people with glaucoma or an enlarged prostate.
- It can cause unusual cravings and changes in behavior in some people.
Used for
- Parkinson's disease
- Extrapyramidal symptoms from nervous system drugs
Dosage forms
- Pill
- Liquid
- Pill
Price
Lowest price
$4.00
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$70.27
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Side effects
The Artane (trihexyphenidyl) FDA package insert doesn’t have numbers about how common side effects are.
46possible side effects
- Difficulty controlling movement18%
- Headache14%
- Accidental injury12%
- Nausea12%
- Falls11%
- Weight loss9%
- Constipation9%
- Low blood pressure9%
- Joint pain8%
- Indigestion7%
- Dizziness7%
- Swelling in arms and legs7%
- Vomiting7%
- Dry mouth6%
- Rash6%
- Sleepiness6%
- Depression5%
- Flu-like symptoms5%
- Abdominal pain5%
- Loss of appetite5%
- Diarrhea5%
- Bruising5%
- Tingling or prickling sensation5%
- Back pain4%
- Cough4%
- Trouble sleeping4%
- Cold or flu4%
- Unusual dreams4%
- Hallucinations4%
- Eyelid problems3%
- Fever3%
- Stomach infection3%
- Stuffy nose3%
- Movement coordination problems3%
- Shortness of breath3%
- Infections3%
- Neck pain3%
- Sweating3%
- Tendon swelling3%
- Uncontrollable muscle movements3%
- Arthritis2%
- Weakness2%
- Gum swelling2%
- Excessive bleeding2%
- Hernia2%
- Muscle weakness2%
Risks and risk factors
- Neuroleptic malignant syndrome
- Abruptly stopping Artane (trihexyphenidyl)
- Drowsiness and dizziness
- Vision problems
- Narrow angle glaucoma
- Dehydration
- Over age 65
- Fever and heat stroke
- Dehydration
- Prolonged exposure to hot conditions
- Alcohol
- Manual laborers
- Psychiatric problems
- Over age 65
- History of mental or psychiatric problems
- Increased blood pressure
- Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats
- Serotonin syndrome
- Tricyclic antidepressants
- Fentanyl
- Tramadol
- Buspirone
- ADHD medicines
- Triptans
- dextromethorphan
- pseudoephedrine
- Falling asleep during the day
- Taking other medicines for Parkinson's disease
- Low blood pressure
- Movement problems
- Taking other medicines for Parkinson's disease
- Lack of impulse control
- Taking other medicines for Parkinson's disease