Compare Artane vs. Mirapex
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats Parkinson's disease.
Artane (trihexyphenidyl) can be used to control tremors if you have Parkinson's, but it can really dry you out and cause other side effects.
Helps with movement problems.
Mirapex (pramipexole) is effective for Parkinson's disease or restless legs syndrome, but can cause extreme drowsiness that affects daily living.
Upsides
- Artane (trihexyphenidyl) can be used with other medicines and in people with advanced Parkinson's who still have tremors.
- Effective by itself for people under 70 with Parkinson's who only have problems with tremors.
- Less severe side effects compared to other medicines for tremors.
- Available as generic.
- Mirapex (pramipexole) may be better for older people with Parkinson's since it causes fewer movement and mental changes than its alternatives.
- Mirapex (pramipexole) comes in extended-release form to help reduce side effects and ease administration.
- Available as a generic so it will be cheaper than similar brand medications.
Downsides
- Not recommended in people over 65 or in people with memory problems.
- Artane (trihexyphenidyl) only calms down tremors because of Parkinson's, but it doesn't treat other symptoms.
- Can't be used in people with glaucoma or an enlarged prostate.
- Mirapex (pramipexole) can be used by itself, but is usually used in combination with other medications to treat Parkinson's.
- Not the best choice if you have kidney problems.
- You cannot suddenly stop taking Mirapex (pramipexole) if you have been taking it for a long time.
Used for
- Parkinson's disease
- Extrapyramidal symptoms from nervous system drugs
- Parkinson's disease
- Restless legs syndrome
- Bipolar depression
Dosage forms
- Pill
- Liquid
- Pill
- Extended release
Price
Lowest price
$6.00
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$67.75
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Side effects
The Artane (trihexyphenidyl) FDA package insert doesn’t have numbers about how common side effects are.
36possible side effects
- Postural hypotension53%
- Muscle rigidity47%
- Extrapyramidal syndrome28%
- Insomnia27%
- Dizziness26%
- Hallucinations17%
- Accidental injury17%
- Dream abnormalities11%
- Confusion10%
- Muscle weakness10%
- Constipation10%
- Sleepiness9%
- Muscle problems8%
- Gait abnormalities7%
- Muscle tenseness7%
- Dry mouth7%
- Memory loss6%
- Urinary frequency6%
- General swelling4%
- Urinary tract infection4%
- Shortness of breath4%
- Accomodation abnormalities4%
- Restlessness3%
- Thinking abnormalities3%
- Chest pain3%
- Malaise3%
- Runny nose3%
- Vision abnormalities3%
- Arthritis3%
- Paranoid reaction2%
- Urinary incontinence2%
- Lung infection2%
- Twitching2%
- Swelling of joints2%
- Peripheral swelling2%
- Skin disorders2%
Risks and risk factors
- Neuroleptic malignant syndrome
- Abruptly stopping Artane (trihexyphenidyl)
- Drowsiness and dizziness
- Vision problems
- Narrow angle glaucoma
- Dehydration
- Over age 65
- Fever and heat stroke
- Dehydration
- Prolonged exposure to hot conditions
- Alcohol
- Manual laborers
- Psychiatric problems
- Over age 65
- History of mental or psychiatric problems
- Impulse control problems
- Problems with concentration
- Taking with alcohol
- Taking other medicines that make you sleepy
- Sleep disorders
- Low blood pressure
- Taking blood pressure medicines
- Kidney problems
- Kidney problems
- Skin cancer
- Parkinson's disease
- Hallucinations and behavior changes
- Age 65 years or older
- History of psychosis
- Advanced Parkinson's disease