Compare Artane vs. Requip
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats Parkinson's disease.
Artane (trihexyphenidyl) can be used to control tremors if you have Parkinson's, but it can really dry you out and cause other side effects.
Helps with movement problems.
Requip (Ropinirole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.
Upsides
- Artane (trihexyphenidyl) can be used with other medicines and in people with advanced Parkinson's who still have tremors.
- Effective by itself for people under 70 with Parkinson's who only have problems with tremors.
- Less severe side effects compared to other medicines for tremors.
- Available as generic.
- In studies, Requip (Ropinirole) when taken by itself or with other medicines, was effective in lowering movement fluctuations for people with Parkinson's disease.
- Requip (Ropinirole) is sometimes preferred over other medicines that treat Parkinson's disease in older people since it causes fewer movement and mental fluctuations.
- Is effective for treating restless leg syndrome.
- Available in a short-acting and a long-acting form.
Downsides
- Not recommended in people over 65 or in people with memory problems.
- Artane (trihexyphenidyl) only calms down tremors because of Parkinson's, but it doesn't treat other symptoms.
- Can't be used in people with glaucoma or an enlarged prostate.
- Requip (Ropinirole) isn't a first-choice treatment for Parkinson's disease. It can be used by itself, but it's usually used with other medicines.
- Requip (Ropinirole) can cause hallucinations in older people.
- Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
- You can't suddenly stop taking Requip (Ropinirole). You'll have to slowly lower your dose, especially if you've been using it for a long time.
Used for
- Parkinson's disease
- Extrapyramidal symptoms from nervous system drugs
Dosage forms
- Pill
- Liquid
- Pill
- Extended release
Price
Lowest price
$4.00
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$20.00
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Side effects
The Artane (trihexyphenidyl) FDA package insert doesn’t have numbers about how common side effects are.
49possible side effects
- Dyskinesia34%
- Nausea30%
- Dizziness26%
- Adverse events24%
- Somnolence20%
- Headache17%
- Falls10%
- Hallucinations10%
- Abdominal pain9%
- Confusion9%
- Upper respiratory tract infection9%
- Hallucination8%
- Increased sweating7%
- Increased drug level7%
- Vomiting7%
- Arthralgia7%
- Abdominal pain/discomfort6%
- Adverse reactions6%
- Tremor6%
- Constipation6%
- Anxiety6%
- Urinary tract infection6%
- Orthostatic hypotension5%
- Dry mouth5%
- Pain5%
- Hypokinesia5%
- Paresthesia5%
- Diarrhea5%
- Amnesia5%
- Nervousness5%
- Vertigo4%
- Edema peripheral4%
- Back pain3%
- Hypertension3%
- Syncope3%
- Paresis3%
- Arthritis3%
- Abnormal dreaming3%
- Dyspnea3%
- Fall/injury2%
- Hypotension2%
- Dysphagia2%
- Flatulence2%
- Increased saliva2%
- Weight decrease2%
- Anemia2%
- Pyuria2%
- Urinary incontinence2%
- Diplopia2%
Risks and risk factors
- Neuroleptic malignant syndrome
- Abruptly stopping Artane (trihexyphenidyl)
- Drowsiness and dizziness
- Vision problems
- Narrow angle glaucoma
- Dehydration
- Over age 65
- Fever and heat stroke
- Dehydration
- Prolonged exposure to hot conditions
- Alcohol
- Manual laborers
- Psychiatric problems
- Over age 65
- History of mental or psychiatric problems
- Impulse control problems
- Driving impairment
- Taking with alcohol
- Taking other medicines that make you less alert
- Low blood pressure
- Taking blood pressure-lowering medicines
- Worsening kidney function
- Current kidney problems
- Skin cancer
- Parkinson's disease
- Hallucinations
- Age 65 years or older