Compare aspirin vs. Acetaminophen with codeine
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Ecotrin (aspirin) can be used for pain and fever relief or heart protection, and is generally very safe and affordable.
Acetaminophen with codeine (acetaminophen / codeine) is a good option to treat pain when over-the-counter medicines aren't enough, but don't take too much acetaminophen (Tylenol) since it can hurt your liver.
- Ecotrin (aspirin) provides the best protection for your heart to prevent heart attacks and stroke with the lowest risk of side effects
- It is available over-the-counter in drugstores on its own and in combination with other cold and flu medications.
- Ecotrin (aspirin) is available as a cheaper, generic form.
- Ecotrin (aspirin) is available in several forms, including tablets, chewable tablets, and suppositories.
- Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relief in a single pill.
- Provides quick relief for mild to moderate pain.
- Good for as-needed pain and control.
- Generally well tolerated, especially if taken with food to lower risk of stomach upset.
- Lower rates of misuse compared to pure opioid medicines.
- Ecotrin (aspirin) is not a preferred medication for treating pain, inflammation, or fever due to the high risk of bleeding.
- Ecotrin (aspirin) increases the risk of bleeding, especially when used with other blood thinner medications like Coumadin (warfarin).
- Dizziness and drowsiness is common, but your body may adjust.
- Many people get constipated taking Acetaminophen with codeine (acetaminophen / codeine).
- All opioid containing medicines have the risk of addiction and withdrawal when used long-term.
- Acetaminophen (Tylenol) has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful since many over-the-counter medicines also have acetaminophen.
- Extended release
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- Reye's Syndrome in children
- Children 18 years or younger
- Children recovering from viral infections
- History of stomach bleeding or ulcers
- Taking Ecotrin (aspirin), NSAIDs, or blood thinners
- Alcohol use
- People 75 years and older taking high dose (325mg) of Ecotrin (aspirin)
- Serious allergic reactions
- Allergy to Ecotrin (aspirin)
- Liver failure and death
- Alcohol use
- Taking over-the-counter medicines with acetaminophen
- History of liver disease
- High risk to children
- Use with other CNS depressants
- Use with alcohol
- Use with benzodiazepines
- Use with other opiates
- Severe allergic reaction