Compare Astepro vs. Zaditor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Astepro (azelastine)

Prescription only

Zaditor (ketotifen)

Over-the-counter
Relieves nasal allergy symptoms.

Astepro (azelastine) is an antihistamine nasal spray that can help with allergy or nasal symptoms.

Relieves itchy eyes due to allergies.

Zaditor (ketotifen) is the first-choice OTC treatment for allergy-related itchy eyes, but it doesn't treat infections and may not help for more serious allergies.

Upsides
  • Astepro (azelastine) is good for relieving nasal symptoms during allergy season.
  • Since Astepro (azelastine) goes in the nose, it's unlikely you'll get side effects anywhere else in your body.
  • Astepro (azelastine) works faster than steroid nasal sprays and can be used as needed.
  • People usually tolerate Astepro (azelastine) well since there are few side effects.
  • Works within minutes to relieve itchy eyes.
  • Available to buy over-the-counter, which makes it cheaper.
  • Can use in children age 3 or older.
  • Unlike pills which can affect your whole body, Zaditor (ketotifen) only affects your eyes, which means it has less side effects than anti-allergy pills.
Downsides
  • Astepro (azelastine) has 200 sprays, but no counter to help keep track of sprays.
  • It can cause a bitter taste in your mouth.
  • Can only use Zaditor (ketotifen) for a short period of time.
  • Administering the medication into the eye safely may be more difficult for some people than taking anti-allergy pills.
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Used for
  • Allergies
Dosage forms
  • Nasal spray
  • Eye drops
Price
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Reviews
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Side effects
5possible side effects
  • Bitter Taste
    8%
  • Nose discomfort
    4%
  • Nosebleeds
    2%
  • Headache
    2%
  • Fatigue
    2%
See more detailed side effects
The Zaditor (ketotifen) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Difficulty concentrating
    • Taking with alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings
  • Allergy to ingredients
  • Risk for eye infection
  • Not to be used with contact lenses
    • Those who wear soft contact lenses
See more detailed risks and warnings