Compare Atripla vs. Stribild

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats HIV infection.

Atripla (efavirenz / emtricitabine / tenofovir) is a convenient 3-in-1 medication used to treat HIV infections. It is a second-line choice due to its high incidence of undesired side effects.

Treats HIV infection.

Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir) is a convenient 4-in-1 medication and one of the first choices used to treat HIV infections.

Upsides
  • Atripla (efavirenz / emtricitabine / tenofovir) combines three medications into one tablet, so it's easy to take.
  • Atripla (efavirenz / emtricitabine / tenofovir) might be an option for HIV treatment if other HIV drug combinations haven't worked for you.
  • There are drug assistance programs available either through the government (AIDS Drug Assistance Program aka. ADAP) or through the drug manufacturer which can help with drug costs and co-pays.
  • First-choice treatment for HIV in patients with good kidney function.
  • One tablet contains four different HIV medications.
  • Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir) is only taken once daily.
  • There are assistance programs available through the manufacturer of Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir) if you need help paying for high insurance copays.
Downsides
  • Atripla (efavirenz / emtricitabine / tenofovir) can increase your risk of depression, and should be used with caution you have a history of seizures or osteoporosis.
  • Women should avoid becoming pregnant while taking Atripla (efavirenz / emtricitabine / tenofovir) and for 12 weeks after stopping Atripla (efavirenz / emtricitabine / tenofovir).
  • Might be inconvenient if used in patients with poorly functioning kidneys because there is no way to adjust the dose of the individual drug components.
  • Can't be used in patients with kidney problems.
  • Can interact with many other drugs.
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Dosage forms
  • Pill
  • Pill
Price
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$2713.58
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Lowest price
$3076.91
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Reviews
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Side effects
13possible side effects
  • Diarrhea
    9%
  • Nausea
    9%
  • Fatigue
    9%
  • Depression
    9%
  • Sinusitis
    8%
  • Upper respiratory tract infections
    8%
  • Dizziness
    8%
  • Rash Event
    7%
  • Headache
    6%
  • Nasopharyngitis
    5%
  • Anxiety
    5%
  • Insomnia
    5%
  • Vomiting
    2%
See more detailed side effects
9possible side effects
  • Nausea
    16%
  • Diarrhea
    12%
  • Abnormal dreams
    9%
  • Headache
    7%
  • Fatigue
    4%
  • Rash
    4%
  • Dizziness
    3%
  • Insomnia
    3%
  • Flatulence
    2%
See more detailed side effects
Risks and risk factors
  • Lactic acidosis | Enlarged, fatty liver
    • Liver disease
    • Women
    • Obesity
  • Cannot be used to treat Hepatitis B Virus (HBV)
    • Hepatitis B Virus infection
  • Mood and behavior changes
    • History of mental health problems
    • History of drug abuse
  • Liver damage
    • History of liver disease
    • Taking alcohol or other drugs that can damage the liver.
  • Bone loss/osteoporosis
    • History of bone fractures
    • Osteoporosis
  • Kidney damage
    • History of kidney damage
    • Taking other medicines that can harm the kidneys
See more detailed risks and warnings
  • Lactic acidosis | Enlarged, fatty liver
    • Liver disease
    • Women
    • Obesity
  • Cannot be used to treat Hepatitis B Virus (HBV)
    • Hepatitis B Virus infection
  • Decreased bone mineral density
    • History of bone fractures
    • Osteoporosis
  • Kidney damage
    • History of kidney damage
    • Taking other medicines that can harm the kidneys
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Drug interactions
    • Taking medicines that interact with Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir)
See more detailed risks and warnings