Compare Atripla vs. Truvada

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats HIV infection.

Atripla (efavirenz / emtricitabine / tenofovir) is a convenient 3-in-1 medication used to treat HIV infections. It is a second-line choice due to its high incidence of undesired side effects.

Works with other medications to treat HIV infection, or works alone to prevent HIV infection.

Truvada (emtricitabine / tenofovir) is a versatile, first-choice HIV medication that is used in combination with other HIV medications to treat and prevent HIV infections.

4.8/ 5 average rating with 16 reviewsforTruvada
Upsides
  • Atripla (efavirenz / emtricitabine / tenofovir) combines three medications into one tablet, so it's easy to take.
  • Atripla (efavirenz / emtricitabine / tenofovir) might be an option for HIV treatment if other HIV drug combinations haven't worked for you.
  • There are drug assistance programs available either through the government (AIDS Drug Assistance Program aka. ADAP) or through the drug manufacturer which can help with drug costs and co-pays.
  • Contains two first-choice medications which can be used in combination with other drugs to treat HIV infection.
  • Truvada (emtricitabine / tenofovir) is also a first-choice option to be used for preventing HIV.
  • Take only once daily, with or without food.
Downsides
  • Atripla (efavirenz / emtricitabine / tenofovir) can increase your risk of depression, and should be used with caution you have a history of seizures or osteoporosis.
  • Women should avoid becoming pregnant while taking Atripla (efavirenz / emtricitabine / tenofovir) and for 12 weeks after stopping Atripla (efavirenz / emtricitabine / tenofovir).
  • Might be inconvenient if used in patients with poorly functioning kidneys because there is no way to adjust the dose of the individual drug components.
  • If you're taking Truvada (emtricitabine / tenofovir) to stop you from getting HIV, you should continue having safe sex since it won't protect you from other sexually transmitted infections.
  • If you're taking Truvada (emtricitabine / tenofovir) to stop you from getting HIV, you have to get blood tests every 3 months to check for overall health and to make sure you don't have HIV or other sexually transmitted infections.
  • People with poorly functioning kidneys shouldn't take Truvada (emtricitabine / tenofovir).
  • Can weaken your bones.
  • If you have HIV as well as Hepatitis B and stop taking Truvada (emtricitabine / tenofovir) suddenly, your hepatitis may get worse.
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Used for
  • HIV treatment
  • HIV prevention
  • Hepatitis B treatment
Dosage forms
  • Pill
  • Pill
Price
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$2713.58
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Lowest price
$1672.61
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Reviews
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16 reviews so far
100%
saidit'sworth it
94%
saiditworked well
0%
saidit'sa big hassle

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Side effects
13possible side effects
  • Diarrhea
    9%
  • Nausea
    9%
  • Fatigue
    9%
  • Depression
    9%
  • Sinusitis
    8%
  • Upper respiratory tract infections
    8%
  • Dizziness
    8%
  • Rash Event
    7%
  • Headache
    6%
  • Nasopharyngitis
    5%
  • Anxiety
    5%
  • Insomnia
    5%
  • Vomiting
    2%
See more detailed side effects
12possible side effects
  • Diarrhea
    9%
  • Nausea
    9%
  • Fatigue
    9%
  • Depression
    9%
  • Stuffy or runny nose
    8%
  • Flu or bronchitis
    8%
  • Dizziness
    8%
  • Rash event
    7%
  • Headache
    6%
  • Common cold
    5%
  • Insomnia
    5%
  • Vomiting
    2%
See more detailed side effects
Risks and risk factors
  • Lactic acidosis | Enlarged, fatty liver
    • Liver disease
    • Women
    • Obesity
  • Cannot be used to treat Hepatitis B Virus (HBV)
    • Hepatitis B Virus infection
  • Mood and behavior changes
    • History of mental health problems
    • History of drug abuse
  • Liver damage
    • History of liver disease
    • Taking alcohol or other drugs that can damage the liver.
  • Bone loss/osteoporosis
    • History of bone fractures
    • Osteoporosis
  • Kidney damage
    • History of kidney damage
    • Taking other medicines that can harm the kidneys
See more detailed risks and warnings
  • Lactic acidosis | Enlarged, fatty liver
    • Liver disease
    • Women
    • Obesity
  • Worsening hepatitis B infection
    • Hepatitis B Virus infection
  • Kidney damage
    • History of kidney damage
    • Concurrent use of other drugs known to harm kidneys
  • Bone loss/osteoporosis
    • History of bone fractures
    • Osteoporosis
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Drug resistance while using pre-exposure prophylaxis (PrEP)
    • Undiscovered HIV infection while on PrEP
See more detailed risks and warnings