Compare Augmentin vs. Minocycline

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats bacterial infections.

Augmentin (amoxicillin / clavulanate) is first-choice antibiotic for most common types of infections. However, it may not work against more serious or uncommon types of infections.

3.9/ 5 average rating with 1034 reviewsforAugmentin
Treats bacterial infections.

Solodyn (Minocycline) is an effective way to treat certain skin infections, acne, and rosacea, but you'll need to use barrier methods of birth control since it can make birth control pills less effective and cause birth defects.

4.0/ 5 average rating with 17 reviewsforMinocycline
Upsides
  • Available as generic product.
  • Available in tablet, capsule, and liquid forms.
  • Used to treat most common types of bacterial infections.
  • Side effects are generally not too bad compared to other antibiotics.
  • Clinical studies show it's effective against MRSA, a common skin infection, and it's commonly used to treat acne and rosacea.
  • Available as a generic, so it should be reasonably priced.
  • Solodyn (Minocycline) is less likely to cause sunburn than other tetracycline antibiotics.
  • Bacteria are less likely to become resistant to Solodyn (Minocycline) than other tetracycline antibiotics.
Downsides
  • Many bacteria have developed resistance to this antibiotic.
  • Can cause diarrhea, nausea, and vomiting.
  • Birth control pills may not work as well to prevent pregnancy when taking this medication.
  • It can make birth control pills less effective, so people should use barrier methods of birth control like condoms or diaphragms while on Solodyn (Minocycline).
  • Can stain your teeth, mouth, and gums if you're using the tablets, or your skin if you're using the topical version, but this is temporary.
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Used for
Dosage forms
  • Pill
  • Chewable tablet
  • Extended release
  • Liquid
  • Pill
  • Extended release
  • Extended release capsule
Price
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Reviews
1034 reviews so far
68%
saidit'sworth it
52%
saiditworked well
13%
saidit'sa big hassle

Have you used Augmentin (amoxicillin / clavulanate)?

Leave a review
17 reviews so far
53%
saidit'sworth it
59%
saiditworked well
18%
saidit'sa big hassle

Have you used Solodyn (Minocycline)?

Leave a review
Side effects
3possible side effects
  • Diarrhea
    9%
  • Nausea
    3%
  • Skin rash and hives
    3%
See more detailed side effects
The Solodyn (Minocycline) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Serious allergic reaction
    • History of penicillin allergy
    • History of multiple allergies
  • Liver damage
    • Existing liver problems
    • Taking other medicines that harm the liver
  • Superinfection
    • Taking Augmentin (amoxicillin / clavulanate) for a long time
    • Older age
    • Taking immunosuppressant medicines
  • Rash
    • Mononucleosis
See more detailed risks and warnings
  • Changes in teeth
    • Age 8 years or younger
  • Decreased effectiveness of birth control pills
    • Using oral birth control pills
  • Diarrhea from a superinfection (an infection that happens after, or in addition to, an earlier infection)
    • Long antibiotic treatment period
  • Rash
  • Sunburn
  • Harm to fetus
    • Women of childbearing age
See more detailed risks and warnings