Compare Avapro vs. Norvasc

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Avapro (irbesartan)

Prescription only

Norvasc (Amlodipine)

Prescription only
Lowers blood pressure.

Avapro (irbesartan) is a good blood pressure-lowering medicine that protects your kidneys and has few side effects.

Lowers blood pressure.

Norvasc (Amlodipine) works well to lower blood pressure and prevent chest pain. You can't miss doses, and you might get persistent swelling.

3.7/ 5 average rating with 443 reviewsforNorvasc
Upsides
  • Avapro (irbesartan) lowers your risk of heart attack and stroke.
  • It works similar to ACE inhibitors (like lisinopril), but it doesn't have the same side effects like coughing and facial swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • It's recommended for people with heart failure since it lowers the risk of death and further damage to your heart.
  • Available in generic, and available with hydrochlorothiazide as a combination tablet.
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Each dose lasts longer than other calcium channel blockers, which keeps blood pressure consistent without big ups and downs.
  • Particularly good at lowering systolic blood pressure (the top number), so it's a good option for older people who can commonly get high blood pressure only in the top number.
Downsides
  • You'll need to get yearly blood tests while taking Avapro (irbesartan) to see how it is affecting your body.
  • It's not safe to use Avapro (irbesartan) if you're pregnant.
  • Avapro (irbesartan) can cause the level of potassium in your blood to go up.
  • You'll need to get medical help if you notice any unusual swelling around your head and neck.
  • Can't be used in children under 18.
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Amlodipine than men.
  • Some people might experience flushing with this medication.
  • You can't miss doses. Stopping Amlodipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • If you have severe heart disease, using Amlodipine might increase your risk of chest pain or heart attack during the time right after starting the medication or raising the dosage.
  • Might not be a good choice if you have liver disease.
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Dosage forms
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Price
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Reviews
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443 reviews so far
58%
saidit'sworth it
50%
saiditworked well
15%
saidit'sa big hassle

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Side effects
3possible side effects
  • Fatigue
    4%
  • Diarrhea
    3%
  • Heartburn
    2%
See more detailed side effects
3possible side effects
  • Fatigue
    5%
  • Nausea
    3%
  • Abdominal pain
    2%
See more detailed side effects
Risks and risk factors
  • Birth defects
    • Women of childbearing age
  • Worsening kidney problems
    • History of kidney problems
  • Swelling in the face and head
    • African descent
  • High potassium levels
    • Current kidney problems
    • Using medicines that increase potassium
    • Using salt substitutes
  • Lightheadedness & dizziness
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
    • Taking diurectics (water pills)
    • Dehydration
See more detailed risks and warnings
  • Low blood pressure
    • Age 65 years or older
  • Heart attack
    • History of heart problems
  • Special dosing requirements
    • Liver disease
  • Foot and leg swelling (edema)
    • History of blood vessel disease
    • History of heart failure
    • History of kidney disease
    • Obesity
See more detailed risks and warnings