Compare Avonex vs. Aubagio

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Aubagio (Teriflunomide)

Prescription only
Lowers the frequency of multiple sclerosis flares and delays disabilty.

Avonex (interferon beta-1a) helps manage multiple sclerosis by reducing flare ups and increasing periods of remission in between, but it may not work for all people.

2.7/ 5 average rating with 33 reviewsforAvonex
Treats relapsing types of multiple sclerosis.

Aubagio (Teriflunomide) significantly improves many symptoms of multiple sclerosis (MS), which may not be seen with some other MS medications.

2.5/ 5 average rating with 23 reviewsforAubagio
Upsides
  • Avonex (interferon beta-1a) decreased MS exacerbations and delayed progression.
  • Avonex (interferon beta-1a) is a first-choice treatment for relapsing MS.
  • Avonex (interferon beta-1a) is safer and provides more convenient dosing (once a week) than some alternative injectable medicines.
  • Aubagio (Teriflunomide) can help reduce the number of flare-ups, slow physical changes, and decrease new brain lesions.
  • Aubagio (Teriflunomide) comes as a pill instead of an injection.
  • You only need to take Aubagio (Teriflunomide) once a day, with or without food.
Downsides
  • Generic is not available, so Avonex (interferon beta-1a) can be expensive.
  • Only available as an injection.
  • Can worsen heart function and depression.
  • Can cause temporary hair loss but it will grow back after stopping.
  • You'll need blood tests before and during treatment to make sure you don't develop any liver problems while taking Aubagio (Teriflunomide).
  • Aubagio (Teriflunomide) may stay in your blood for up to 2 years after taking it, so it is important to discuss a plan with your doctor in case it's not the right medication for you.
  • You can't take Aubagio (Teriflunomide) if you're pregnant, have severe liver damage, or are currently taking Arava (leflunomide).
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Used for
Dosage forms
  • Injection
  • Pill
Price
Lowest price
$6864.89
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Reviews
33 reviews so far
36%
saidit'sworth it
24%
saiditworked well
33%
saidit'sa big hassle

Have you used Avonex (interferon beta-1a)?

Leave a review
23 reviews so far
43%
saidit'sworth it
26%
saiditworked well
30%
saidit'sa big hassle

Have you used Aubagio (Teriflunomide)?

Leave a review
Side effects
29possible side effects
  • Headache
    57%
  • Flu-like symptoms
    49%
  • Muscle pain
    28%
  • Weakness
    24%
  • Pain
    23%
  • Nausea
    23%
  • Fever
    20%
  • Chills
    19%
  • Depression
    18%
  • Bladder infection
    17%
  • Dizziness
    14%
  • Nose or throat infection
    14%
  • Sinus infection
    14%
  • Joint pain
    9%
  • Stomach pain
    8%
  • Injection site pain
    8%
  • Bronchitis
    8%
  • Infection
    7%
  • Injection site inflammation
    6%
  • Injection site bruising
    6%
  • Chest pain
    5%
  • Migraine
    5%
  • Hair loss
    4%
  • Eye disorder
    4%
  • Low iron
    4%
  • Injection site reaction
    3%
  • Toothache
    3%
  • Abnormal components in urine
    3%
  • Dilation of blood vessels
    2%
See more detailed side effects
9possible side effects
  • Headache
    18%
  • Abnormal liver enzymes
    13%
  • Diarrhea
    13%
  • Hair loss
    10%
  • Nausea
    8%
  • Burning or prickling sensation in hands, arms, legs, or feet
    8%
  • Joint pain
    8%
  • Low white blood cells
    4%
  • High blood pressure
    3%
See more detailed side effects
Risks and risk factors
  • Suicidal thoughts or behavior
    • History of depression or mental illness
  • Liver damage
    • Alcohol use
    • Taking other medicines that cause liver injury
    • History of liver disease
  • Risk of worsening heart function
    • History of heart failure
  • Injection site reaction
  • Seizures
    • History of seizures
  • Low blood counts
See more detailed risks and warnings
  • Liver problems
    • Taking medicines that affect your liver or cause liver injury
  • Harm to unborn baby
  • Slow elimination from body
  • Serious skin reactions
  • Numbness in extremities (hands and feet)
    • Age 60 or older
    • Taking medicines that are toxic to the nervous system
    • Diabetes
  • Risk of serious infections
    • Taking other drugs that weaken your immune system
    • Age 60 or older
    • Weak immune system
See more detailed risks and warnings