Compare Avonex vs. Betaseron

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Lowers the frequency of multiple sclerosis flares and delays disabilty.

Avonex (interferon beta-1a) helps manage multiple sclerosis by reducing flare ups and increasing periods of remission in between, but it may not work for all people.

2.7/ 5 average rating with 33 reviewsforAvonex
Helps prevent multiple sclerosis flare-ups.

Betaseron (Interferon beta-1b) is an injection that effectively treats relapsing multiple sclerosis. It's used every other day and has relatively few side effects.

3.5/ 5 average rating with 21 reviewsforBetaseron
Upsides
  • Avonex (interferon beta-1a) decreased MS exacerbations and delayed progression.
  • Avonex (interferon beta-1a) is a first-choice treatment for relapsing MS.
  • Avonex (interferon beta-1a) is safer and provides more convenient dosing (once a week) than some alternative injectable medicines.
  • Betaseron (Interferon beta-1b) sometimes works better than other similar injectable medications.
  • Betaseron (Interferon beta-1b) may be less expensive than its alternatives.
Downsides
  • Generic is not available, so Avonex (interferon beta-1a) can be expensive.
  • Only available as an injection.
  • Can worsen heart function and depression.
  • Betaseron (Interferon beta-1b) only comes as an injection, so you'll need to give yourself shots.
  • You may need to get blood work done regularly to monitor your blood cell counts.
  • Betaseron (Interferon beta-1b) needs to be used every other day, unlike similar medications that don't have to be taken as frequently.
  • Betaseron (Interferon beta-1b) isn't as effective as its alternative that's given in the hospital as an infusion.
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Used for
Dosage forms
  • Injection
  • Injection
Price
Lowest price
$6750.97
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Lowest price
$6268.54
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Reviews
33 reviews so far
36%
saidit'sworth it
24%
saiditworked well
33%
saidit'sa big hassle

Have you used Avonex (interferon beta-1a)?

Leave a review
21 reviews so far
57%
saidit'sworth it
48%
saiditworked well
38%
saidit'sa big hassle

Have you used Betaseron (Interferon beta-1b)?

Leave a review
Side effects
29possible side effects
  • Headache
    57%
  • Flu-like symptoms
    49%
  • Muscle pain
    28%
  • Weakness
    24%
  • Pain
    23%
  • Nausea
    23%
  • Fever
    20%
  • Chills
    19%
  • Depression
    18%
  • Bladder infection
    17%
  • Dizziness
    14%
  • Nose or throat infection
    14%
  • Sinus infection
    14%
  • Joint pain
    9%
  • Stomach pain
    8%
  • Injection site pain
    8%
  • Bronchitis
    8%
  • Infection
    7%
  • Injection site inflammation
    6%
  • Injection site bruising
    6%
  • Chest pain
    5%
  • Migraine
    5%
  • Hair loss
    4%
  • Eye disorder
    4%
  • Low iron
    4%
  • Injection site reaction
    3%
  • Toothache
    3%
  • Abnormal components in urine
    3%
  • Dilation of blood vessels
    2%
See more detailed side effects
24possible side effects
  • Injection site reaction
    78%
  • Flu-like symptoms
    56%
  • Weakness
    53%
  • Headache
    50%
  • Pain
    42%
  • Rigid muscles
    40%
  • Fever
    31%
  • Muscle pain
    23%
  • Trouble sleeping
    21%
  • Rash
    21%
  • Chills
    21%
  • Lack of coordination
    17%
  • Abdominal pain
    16%
  • Swelling in the limbs
    12%
  • Urinary urgency
    11%
  • Skin disorder
    10%
  • Uterine bleeding
    9%
  • Chest pain
    9%
  • Impotence
    8%
  • Enlarged lymph nodes
    6%
  • High blood pressure
    6%
  • Shortness of breath
    6%
  • Malaise
    6%
  • Injection site tissue death
    4%
See more detailed side effects
Risks and risk factors
  • Suicidal thoughts or behavior
    • History of depression or mental illness
  • Liver damage
    • Alcohol use
    • Taking other medicines that cause liver injury
    • History of liver disease
  • Risk of worsening heart function
    • History of heart failure
  • Injection site reaction
  • Seizures
    • History of seizures
  • Low blood counts
See more detailed risks and warnings
  • Liver damage
    • Alcohol use
    • Taking other drugs that can hurt your liver
    • Active, or history of, liver disease
  • Serious injection site reactions
  • Suicidal thoughts or behavior
    • History of depression or mental illness
  • Heart problems
    • History of or current heart disease
  • Seizures
    • History of seizures
  • Lupus
See more detailed risks and warnings