Compare Axiron vs. Testopel

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Axiron (Testosterone Topical Solution)

Prescription only

Testopel (Testosterone Implant)

Prescription only

Treats low testosterone.

This testosterone topical solution is a convenient topical form of hormone replacement that's less likely to rub off on other people you come into contact with, but it's not available as a generic yet.

Treats low testosterone.

The testosterone implant is a good option for long-term testosterone therapy, but it can be expensive, and it's really important that you get the right dose so your doctor doesn't have to remove pellets.

Upsides

You're less likely with this formulation to transfer testosterone topical solution to another person since this is applied to the armpits -- unlike some other forms of topical testosterone.
You can use your regular deodorant or antiperspirant, but just make sure to apply that first before using testosterone topical solution.

Your doctor will give this shot to you every 3 months, so you don't have to worry about administering it yourself like some testosterone injections.
Unlike topical forms of testosterone, you don't have to worry about accidentally transferring this medication to another person's skin.

Downsides

Only available as brand name.
You have to wait at least 2 hours after applying testosterone topical solution before you can swim or bathe, otherwise your body won't absorb the entire amount.

Not available in generic form, so it can be more expensive.
Your doctor has to calculate your dose for 3 months. If it ends up being too much, the doctor might have to remove some of the implant pellets.
The pellets can come out, although this is extremely rare.

Used for