Compare Aygestin vs. Provera

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Regulates your menstrual cycle and treats irregular bleeding.

Aygestin (norethindrone) regulates the menstrual cycle and treats heavy or irregular vaginal bleeding. It's easy to take and isn't expensive.

2.7/ 5 average rating with 30 reviewsforAygestin
Regulates your menstrual cycle and supplements estrogen treatments for menopause.

Provera (Medroxyprogesterone) works well to regulate your menstrual cycle and stop irregular bleeding. It also protects the uterus from estrogen's harmful effects.

Upsides
  • Helps to regulate your period.
  • Decreases bleeding from hormone imbalance.
  • Available as a generic medication, so it costs less.
  • Provera (Medroxyprogesterone) can be used to treat multiple hormone problems in women.
  • After menopause, taking estrogen raises your risk of uterine cancer. However, taking progesterone, like in Provera (Medroxyprogesterone), along with estrogen gives you the positive effects of estrogen, but also prevents it from damaging your uterus.
  • Women taking an estrogen/progestin combination medications have a lower risk of uterine cancer.
Downsides
  • Can make you gain weight.
  • Higher risk of blood clots.
  • Not for people who are post-menopausal, pregnant, or breast-feeding.
  • Can cause a lot of side effects.
  • You can't take Provera (Medroxyprogesterone) if you've had a hysterectomy (your uterus removed). You also can't take it if you're pregnant or breastfeeding, have unusual vaginal bleeding, or have a history of blood clots, certain kinds of cancer, stroke, heart attack, liver problems, or bleeding problems.
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Used for
  • Pain caused by endometriosis
  • Balances hormones in women who don't have regular monthly periods
  • Balances hormones in women who have unusual monthly periods
  • In vitro fertilization
  • Amenorrhea
  • Abnormal uterine bleeding
  • Prevention of uterine cancer in women taking estrogen
  • Endometriosis
  • Premenstrual syndrome
  • Breast cancer
  • Uterine cancer
  • Pelvic congestion syndrome
  • Birth control (male)
  • Hirsutism
  • Loss of appetite
  • Osteoporosis
  • Renal cell carcinoma
Dosage forms
  • Pill
  • Pill
Price
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Reviews
30 reviews so far
40%
saidit'sworth it
23%
saiditworked well
23%
saidit'sa big hassle

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Side effects
The Aygestin (norethindrone) FDA package insert doesn’t have numbers about how common side effects are.
The Provera (Medroxyprogesterone) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Increased risk of blood clots and stroke
    • Personal or family history of blood clots
    • Smoking
    • Obesity
    • Systemic lupus erythematosus (SLE)
  • Abnormal vision changes
  • Depression
    • History of depression
  • Changes in blood sugar levels
    • Diabetes
  • Liver problems
    • History of liver problems
  • High cholesterol levels
    • High cholesterol levels
See more detailed risks and warnings
  • Breast cancer
    • Personal or family history of breast cancer
  • Ovarian cancer
    • Family history of ovarian cancer
  • Increased risk of blood clots and stroke
    • Personal or family history of blood clots
    • Smoking
    • Obesity
    • Hypertension
    • Diabetes
    • High cholesterol
    • Systemic lupus erythematosus (SLE)
  • Depression
    • History of depression
  • Liver problems
    • History of liver problems
  • Harm to fetus
    • Women of childbearing age
See more detailed risks and warnings