Compare AzaSite vs. Ciloxan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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AzaSite (azithromycin)

Prescription only

Ciloxan (ciprofloxacin)

Prescription only
Treats pink eye.

AzaSite (azithromycin) effectively treats pink eye and requires you to place less drops into your eye compared to similar medications, but it can be expensive.

Treats eye infections.

Ciloxan (ciprofloxacin) effectively treats pink eye and corneal ulcers caused by a variety of bacteria, but might not be good for more serious infections.

Upsides
  • Less frequent applications make AzaSite (azithromycin) more convenient to use than similar medicines.
  • Since you apply AzaSite (azithromycin) directly to the eye(s), there are minimal systemic side effects.
  • Ciloxan (ciprofloxacin) has a high success rate in treating people with pink eye and corneal ulcers.
  • Has fewer side effects compared to alternative oral medications since Ciloxan (ciprofloxacin) is applied directly to the eyes.
  • Ciloxan (ciprofloxacin) eyedrops are available in an inexpensive, generic form.
  • The ointment helps to lubricate and soothe the eye.
  • Applied less frequently than other eye drops.
Downsides
  • AzaSite (azithromycin) is not available as a generic and costs significantly more than similar medicines.
  • Directly applying AzaSite (azithromycin) to the eyes can irritate them.
  • Ciloxan (ciprofloxacin) drops require frequent applications, especially during the first few days of treatment.
  • Ciloxan (ciprofloxacin) ointment is expensive because a generic is not available.
  • The ointment can cause blurry vision for a few minutes after applying.
  • Application of Ciloxan (ciprofloxacin) can temporarily irritate the eyes.
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Used for
Dosage forms
  • Eye drops
  • Eye drops
  • Eye ointment
Price
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Reviews
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Side effects
1possible side effects
  • Eye irritation
    2%
See more detailed side effects
The Ciloxan (ciprofloxacin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Allergy to ingredients
    • Allergies to systemic azithromycin.
  • Risk for eye infection
  • Not to be used with contact lenses
  • For use topically in the eyes only
  • New infection
    • Prolonged use
See more detailed risks and warnings
  • Allergy to ingredients
    • Allergies to quinolone antibiotics such as Levaquin and Cipro
  • Risk for contamination
  • Not to be used with contact lenses
  • Risk of infection
    • Prolonged use
See more detailed risks and warnings