Compare Azilect vs. Mirapex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Azilect (rasagiline)

Prescription only

Mirapex (pramipexole)

Prescription only
Treats Parkinson's disease.

Azilect (rasagiline) is one of the recommended medicines to treat Parkinson's disease. It is now available in generic, which makes it more affordable for people without insurance.

Helps with movement problems.

Mirapex (pramipexole) is effective for Parkinson's disease or restless legs syndrome, but can cause extreme drowsiness that affects daily living.

Upsides
  • Azilect (rasagiline) is one of the go-to medicines for Parkinson's disease. It can be used in early and late stages of the disease.
  • Taking Azilect (rasagiline) by itself can help slow down Parkinson's disease, but it works better when it's given with other medicines.
  • Azilect (rasagiline) is available as generic as well as brand name, so there are usually lower out-of-pocket costs for you with insurance.
  • Mirapex (pramipexole) may be better for older people with Parkinson's since it causes fewer movement and mental changes than its alternatives.
  • Mirapex (pramipexole) comes in extended-release form to help reduce side effects and ease administration.
  • Available as a generic so it will be cheaper than similar brand medications.
Downsides
  • It can cause unusual cravings and changes in behavior in some people.
  • Mirapex (pramipexole) can be used by itself, but is usually used in combination with other medications to treat Parkinson's.
  • Not the best choice if you have kidney problems.
  • You cannot suddenly stop taking Mirapex (pramipexole) if you have been taking it for a long time.
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Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
Lowest price
$196.25
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Lowest price
$129.79
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Reviews
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Side effects
46possible side effects
  • Difficulty controlling movement
    18%
  • Headache
    14%
  • Accidental injury
    12%
  • Nausea
    12%
  • Falls
    11%
  • Weight loss
    9%
  • Constipation
    9%
  • Low blood pressure
    9%
  • Joint pain
    8%
  • Indigestion
    7%
  • Dizziness
    7%
  • Swelling in arms and legs
    7%
  • Vomiting
    7%
  • Dry mouth
    6%
  • Rash
    6%
  • Sleepiness
    6%
  • Depression
    5%
  • Flu-like symptoms
    5%
  • Abdominal pain
    5%
  • Loss of appetite
    5%
  • Diarrhea
    5%
  • Bruising
    5%
  • Tingling or prickling sensation
    5%
  • Back pain
    4%
  • Cough
    4%
  • Trouble sleeping
    4%
  • Cold or flu
    4%
  • Unusual dreams
    4%
  • Hallucinations
    4%
  • Eyelid problems
    3%
  • Fever
    3%
  • Stomach infection
    3%
  • Stuffy nose
    3%
  • Movement coordination problems
    3%
  • Shortness of breath
    3%
  • Infections
    3%
  • Neck pain
    3%
  • Sweating
    3%
  • Tendon swelling
    3%
  • Uncontrollable muscle movements
    3%
  • Arthritis
    2%
  • Weakness
    2%
  • Gum swelling
    2%
  • Excessive bleeding
    2%
  • Hernia
    2%
  • Muscle weakness
    2%
See more detailed side effects
36possible side effects
  • Postural hypotension
    53%
  • Muscle rigidity
    47%
  • Extrapyramidal syndrome
    28%
  • Insomnia
    27%
  • Dizziness
    26%
  • Hallucinations
    17%
  • Accidental injury
    17%
  • Dream abnormalities
    11%
  • Confusion
    10%
  • Muscle weakness
    10%
  • Constipation
    10%
  • Sleepiness
    9%
  • Muscle problems
    8%
  • Gait abnormalities
    7%
  • Muscle tenseness
    7%
  • Dry mouth
    7%
  • Memory loss
    6%
  • Urinary frequency
    6%
  • General swelling
    4%
  • Urinary tract infection
    4%
  • Shortness of breath
    4%
  • Accomodation abnormalities
    4%
  • Restlessness
    3%
  • Thinking abnormalities
    3%
  • Chest pain
    3%
  • Malaise
    3%
  • Runny nose
    3%
  • Vision abnormalities
    3%
  • Arthritis
    3%
  • Paranoid reaction
    2%
  • Urinary incontinence
    2%
  • Lung infection
    2%
  • Twitching
    2%
  • Swelling of joints
    2%
  • Peripheral swelling
    2%
  • Skin disorders
    2%
See more detailed side effects
Risks and risk factors
  • Increased blood pressure
    • Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats
  • Serotonin syndrome
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    • ADHD medicines
    • Triptans
    • dextromethorphan
    • pseudoephedrine
  • Falling asleep during the day
    • Taking other medicines for Parkinson's disease
  • Low blood pressure
  • Movement problems
    • Taking other medicines for Parkinson's disease
  • Lack of impulse control
    • Taking other medicines for Parkinson's disease
See more detailed risks and warnings
  • Impulse control problems
  • Problems with concentration
    • Taking with alcohol
    • Taking other medicines that make you sleepy
    • Sleep disorders
  • Low blood pressure
    • Taking blood pressure medicines
  • Kidney problems
    • Kidney problems
  • Skin cancer
    • Parkinson's disease
  • Hallucinations and behavior changes
    • Age 65 years or older
    • History of psychosis
    • Advanced Parkinson's disease
See more detailed risks and warnings
Learn more about Azilect (rasagiline)
Learn more about Mirapex (pramipexole)