Compare baclofen vs. Flexeril
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Relaxes your muscles.
Lioresal (baclofen) is a first choice treatment for muscle spasticity caused by multiple sclerosis or spinal cord injuries, but it's not recommended for other types of muscle spasms.
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3.5/ 5 average rating with 33 reviewsforbaclofen
Relaxes your muscles.
Flexeril (cyclobenzaprine) is widely used to treat muscle spasms and is available as a generic, but it shouldn't be used long-term.
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3.5/ 5 average rating with 1064 reviewsforFlexeril
Upsides
- A better option for seniors compared to other muscle relaxants since it has fewer side effects than other similar medicines.
- Lioresal (baclofen) is available as a generic and is a relatively inexpensive medication.
- Can relieve pain associated with muscle spasms.
- Available as a generic medication.
- Can be used by pregnant women, but talk to your doctor about it first.
Downsides
- Except for specific muscle spasms caused by brain injury or multiple sclerosis, Lioresal (baclofen) is not a recommended medicine.
- If you've been taking Lioresal (baclofen) regularly for a long time, you'll need to get off of it slowly.
- Lioresal (baclofen) can make you sleepy.
- If you've had a stroke, Lioresal (baclofen) may not work as well, and you're more likely to experience side effects.
- Can cause dizziness and sleepiness.
- Not meant for long-term therapy.
- Not recommended in elderly patients, people with glaucoma, or in people with heart conditions (like rhythm problems, heart failure, or recent heart attack).
- Can make you have dry mouth.
- Not effective for muscle spasms caused by brain or spinal injuries.
Used for
Dosage forms
- Pill
- Pill
- Liquid
Price
Lowest price
$13.49
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$213.06
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Reviews
33 reviews so far
61%
saidit'sworth it
55%
saiditworked well
15%
saidit'sa big hassle
Have you used Lioresal (baclofen)?
Leave a review1064 reviews so far
66%
saidit'sworth it
37%
saiditworked well
14%
saidit'sa big hassle
Have you used Flexeril (cyclobenzaprine)?
Leave a reviewSide effects
Risks and risk factors
- Withdrawal symptoms
- Stopping Lioresal (baclofen) too quickly
- Driving impairment
- Taking with alcohol
- Taking other medicines that make you less alert
- Age 65 or greater
- Seizures
- Higher dose
- Using other medicines that can cause seizures
- History of seizures
- Alcoholism
- Eating disorders
- Brain infections
- Serotonin syndrome
- Taking monoamine oxidase inhibitors (MAOI)
- Taking other medications for your mood
- Dizziness and sleepiness
- Alcohol or drug use
- Age over 65 years
- Heart attack or stroke
- Recent heart attack
- Heart rhythm problems
- Heart failure
- Dehydration
- Older than 65 years
- Dehydration
- Overactive Thyroid
- Overactive thyroid