Compare baclofen vs. Soma

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT

Lioresal (baclofen)

Prescription only

Soma (carisoprodol)

Prescription only
Relaxes your muscles.

Lioresal (baclofen) is a first choice treatment for muscle spasticity caused by multiple sclerosis or spinal cord injuries, but it's not recommended for other types of muscle spasms.

3.5/ 5 average rating with 33 reviewsforbaclofen
Relaxes your muscles.

Soma (carisoprodol) is used for muscle spasms and muscle pain but it's not considered a first-choice treatment and not meant for long-term therapy.

3.5/ 5 average rating with 220 reviewsforSoma
Upsides
  • A better option for seniors compared to other muscle relaxants since it has fewer side effects than other similar medicines.
  • Lioresal (baclofen) is available as a generic and is a relatively inexpensive medication.
  • Patients treated with Soma (carisoprodol) experienced improvement in function.
  • Available in generic.
  • Available in two different strengths.
Downsides
  • Except for specific muscle spasms caused by brain injury or multiple sclerosis, Lioresal (baclofen) is not a recommended medicine.
  • If you've been taking Lioresal (baclofen) regularly for a long time, you'll need to get off of it slowly.
  • Lioresal (baclofen) can make you sleepy.
  • If you've had a stroke, Lioresal (baclofen) may not work as well, and you're more likely to experience side effects.
  • Not first choice for treating muscle spasms or muscle pain, because it can cause dependence.
  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy, because it hasn't been shown to be effective after taking it for a short period.
  • Can cause withdrawal symptoms if you stop taking it suddenly.
ADVERTISEMENT
Used for
Dosage forms
  • Pill
  • Pill
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
33 reviews so far
61%
saidit'sworth it
55%
saiditworked well
15%
saidit'sa big hassle

Have you used Lioresal (baclofen)?

Leave a review
220 reviews so far
61%
saidit'sworth it
39%
saiditworked well
9%
saidit'sa big hassle

Have you used Soma (carisoprodol)?

Leave a review
Side effects
1possible side effects
  • Drowsiness
    63%
See more detailed side effects
3possible side effects
  • Drowsiness
    13%
  • Dizziness
    8%
  • Headache
    5%
See more detailed side effects
Risks and risk factors
  • Withdrawal symptoms
    • Stopping Lioresal (baclofen) too quickly
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Age 65 or greater
  • Seizures
    • Higher dose
    • Using other medicines that can cause seizures
    • History of seizures
    • Alcoholism
    • Eating disorders
    • Brain infections
See more detailed risks and warnings
  • Sleepiness and dizziness
    • Taking other medications that also cause sleepiness
    • Recreational drug use
    • Excessive alcohol use
    • Elderly
  • Abuse, dependence and withdrawal
    • Prior history of drug abuse
    • Taking Soma (carisoprodol) for a long time
  • Seizures
    • Prior history of overdoses of drugs of abuse, recreational drugs, or alcohol
See more detailed risks and warnings