Compare baclofen vs. Vesicare

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Lioresal (baclofen)

Prescription only

Vesicare (solifenacin)

Prescription only
Relaxes your muscles.

Lioresal (baclofen) is a first choice treatment for muscle spasticity caused by multiple sclerosis or spinal cord injuries, but it's not recommended for other types of muscle spasms.

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3.5/ 5 average rating with 33 reviewsforbaclofen
Treats overactive bladder.

Vesicare (solifenacin) is a good choice for treatment of overactive bladder if exercises and other behavioral methods haven't worked.

Upsides
  • A better option for seniors compared to other muscle relaxants since it has fewer side effects than other similar medicines.
  • Lioresal (baclofen) is available as a generic and is a relatively inexpensive medication.
  • Vesicare (solifenacin) helps you to urinate less often.
  • Its once daily dosing is more convenient than other medicines that work like it.
Downsides
  • Except for specific muscle spasms caused by brain injury or multiple sclerosis, Lioresal (baclofen) is not a recommended medicine.
  • If you've been taking Lioresal (baclofen) regularly for a long time, you'll need to get off of it slowly.
  • Lioresal (baclofen) can make you sleepy.
  • If you've had a stroke, Lioresal (baclofen) may not work as well, and you're more likely to experience side effects.
  • Can cause drowsiness and increase the risk of falls, especially in the elderly.
  • Not a good option if you have untreated, narrow-angle glaucoma.
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Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price
$12.86
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Lowest price
$379.61
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Reviews
33 reviews so far
61%
saidit'sworth it
55%
saiditworked well
15%
saidit'sa big hassle

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Side effects
1possible side effects
  • Drowsiness
    63%
See more detailed side effects
8possible side effects
  • Dry mouth
    11%
  • Constipation
    5%
  • Blurry vision
    4%
  • Urinary tract infection
    3%
  • Nausea
    2%
  • Upper abdominal pain
    2%
  • Flu
    2%
  • Dizziness
    2%
See more detailed side effects
Risks and risk factors
  • Withdrawal symptoms
    • Stopping Lioresal (baclofen) too quickly
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Age 65 or greater
  • Seizures
    • Higher dose
    • Using other medicines that can cause seizures
    • History of seizures
    • Alcoholism
    • Eating disorders
    • Brain infections
See more detailed risks and warnings
  • Tissue swelling
  • Drowsiness
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • People age 65 or older
  • Vision changes
    • Glaucoma
  • Urinary blockage
    • Bladder outflow obstruction
  • Worsening side effects
    • History of kidney problems
    • People age 65 or older
  • Temperature dysregulation
    • Outside in hot weather
    • Dehydrated
    • Exercising
    • Added people 65 and older per Beer's Criteria
    • People age 65 and older
See more detailed risks and warnings
Learn more about Lioresal (baclofen)
Learn more about Vesicare (solifenacin)