Compare Baraclude vs. Pegasys

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats hepatitis B.

Baraclude (entecavir) works well to treat hepatitis B, but tenofovir (Viread or Vemlidy) might be the better choice if you’ve taken other oral medicines for hepatitis B before or also have HIV.

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Upsides
  • Baraclude (entecavir) is a first-choice medicine to treat hepatitis B.
  • Safer option for people with kidney damage.
  • Side effects are mild and short-lived.
  • Can be used in children as young as 2 years old.
  • Conveniently comes as a liquid for children and people who struggle to swallow pills.
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Downsides
  • Doesn't cure hepatitis B.
  • Might not be a good choice for people who’ve taken Epivir HBV (lamivudine) in the past due to the possibility of resistance.
  • Not the first choice for people with both hepatitis B and HIV.
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Used for
  • Hepatitis B
  • Prevention of hepatitis B reinfection after liver transplant
  • Active type B viral hepatitis
  • Chronic Hepatitis C
  • Chronic
  • In patients with compensated liver disease - HIV infection Hepatitis C
  • Chronic
  • Interferon alfa-naive
  • With compensated liver disease
  • Hepatitis C
  • Chronic
  • Interferon alfa/ribavirin nonresponders
Dosage forms
  • Pill
  • Liquid
  • Injection
Price
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Reviews
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Side effects
2possible side effects
  • Headache
    4%
  • Tiredness
    3%
See more detailed side effects
The Pegasys (Peginterferon Alfa-2A) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Worsening of hepatitis B infection
    • Stopping Baraclude (entecavir)
  • Hepatitis B and HIV co-infection
    • HIV infection
  • Buildup of acid in the blood and swollen, fatty liver
    • Obesity
    • History of liver disease
    • Women
    • Taking Baraclude (entecavir) for a long time
See more detailed risks and warnings
No information currently available