Compare Benadryl vs. Rhinocort Aqua

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Benadryl (Diphenhydramine)

Prescription or OTC
Treats allergy symptoms and helps you sleep.

Benadryl (Diphenhydramine) is great for allergies, but curl up on the couch after taking it and get ready for a nap.

4.1/ 5 average rating with 294 reviewsforBenadryl
Relieves nasal allergy symptoms.

Rhinocort Aqua (Budesonide) is a steroid nasal spray that works best when used regularly for your nasal allergy symptoms.

Upsides
  • Benadryl (Diphenhydramine) is often better than other antihistamines at treating allergy symptoms and hives.
  • It can provide quick relief of allergy symptoms for both kids and adults.
  • It makes you sleepy, so it'll help if your allergies are bothering you at night.
  • The effects wear off in 4 to 6 hours, so side effects don't last that long.
  • It comes as a tablet, capsule, liquid, and quick dissolving tablet.
  • Rhinocort Aqua (Budesonide) lowers the number of nasal symptoms you'll get during allergy season.
  • Most people don't have many side effects since it works in the nose and doesn't affect the rest of your body.
  • Doesn't make you drowsy or dizzy.
Downsides
  • Benadryl (Diphenhydramine) makes you more tired than Claritin, Allegra, or Zyrtec.
  • You shouldn't drive after taking Benadryl (Diphenhydramine) until you know how it affects you.
  • Talk to a pediatrician before giving Benadryl (Diphenhydramine) to a child.
  • It can increase the risk of falls, so elderly people shouldn't use Benadryl (Diphenhydramine).
  • Don't use Benadryl (Diphenhydramine) if you are breastfeeding.
  • Needs to be used everyday to work, so it can't be used as needed.
  • Can hace an unpleasant smell or taste.
  • It's good for 120 sprays, but there isn't a counter to help you keep track of sprays.
  • Can't be used in kids younger than age 6 years.
  • Need a prescription to get Rhinocort Aqua (Budesonide).
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Used for
Dosage forms
  • Pill
  • Oral solution
  • Cream, gel, or ointment
  • Nasal spray
Price
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Reviews
294 reviews so far
86%
saidit'sworth it
59%
saiditworked well
8%
saidit'sa big hassle

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Side effects
The Benadryl (Diphenhydramine) FDA package insert doesn’t have numbers about how common side effects are.
5possible side effects
  • Epistaxis
    8%
  • Pharyngitis
    4%
  • Bronchospasm
    2%
  • Coughing
    2%
  • Nasal Irritation
    2%
See more detailed side effects
Risks and risk factors
  • Overdose
    • Using other drugs with the same ingredients
  • Increased side effects
    • Age 65 years or older
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Hyperactivity
    • Children age 6 years and younger
  • Trouble urinating
    • Enlarged prostate
    • History of bladder problems
  • Vision changes
    • Glaucoma
  • Breastfeeding
    • Nursing mothers
See more detailed risks and warnings
  • Changes to your nose
    • Long-term use
  • Poor wound healing
    • Surgery or trauma to the nose or sinuses
  • Increased risk of infections
    • Long-term use
    • Untreated infections
  • Glaucoma and cataracts
    • Long-term use
  • Withdrawal
    • Long-term use
  • Decrease in growth in children and teenagers
    • Long-term use
    • Taking more than recommended dose
See more detailed risks and warnings