Compare Benzamycin vs. Erygel

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Topical treatment for acne and pimples.

Benzamycin (benzoyl peroxide / erythromycin) is a common affordable treatment for acne and pimples, but it can stain clothing and hair.

3.4/ 5 average rating with 146 reviewsforBenzamycin
Topical treatment for acne.

Akne-Mycin (Erythromycin) is a very common acne treatment you apply to the skin that may work better when combined with other topical medicines.

3.4/ 5 average rating with 93 reviewsforErygel
Upsides
  • The combination of medicines in Benzamycin (benzoyl peroxide / erythromycin) works better to reduce bacteria in oil glands and improve overall appearance of acne than either medicine alone.
  • Combining an antibiotic with benzoyl peroxide lowers the chances of Benzamycin (benzoyl peroxide / erythromycin) not working as well over time (known as resistance).
  • Can be used in combination with acne pill medicine if your doctor thinks you need it.
  • A generic form of Benzamycin (benzoyl peroxide / erythromycin) is available to help lower cost.
  • Applying erythromycin to the skin reduces the amount of acne bacteria and "calms" the skin down (lowers the inflammatory response) in acne.
  • Available in a gel formulation which may be better if your skin is very oily.
  • Better choice if you're pregnant. erythromycin is categorized as pregnancy Category B (likely safe) as compared to similar topical medicines that are Category C (weigh risks vs benefits).
Downsides
  • Benzamycin (benzoyl peroxide / erythromycin) may not work for everyone. Like with any acne medicine, you may have to try different medicines before finding the one that works for you.
  • You have to apply this twice a day. With some other medicines, you may only need to apply once a day.
  • Is generally only effective for mild to moderate acne. If you have severe acne, you may need an oral medication.
  • The most common form of Benzamycin (benzoyl peroxide / erythromycin) needs to be stored in the fridge and is only good for 3 months even if you have medicine remaining in the container.
  • There's a risk of irritation with anything you apply to your skin and this is no different. erythromycin, like other topical antibiotics, can cause skin irritation and may appear as redness, peeling, abnormal dryness or stinging, tightening, or burning sensations.
  • It's rare, that a serious allergic reaction would occur, but it's a good idea to test a small area of skin before using on any larger or sensitive areas
  • Studies show it works better when combined with other topical medicines to fight acne and reduce the risk of it losing its effectiveness over time.
  • Can cause severe inflammation of the large intestine (pseudomembranous colitis)
  • Stop using if you don't notice any improvement in your acne after 6-8 weeks. The most time you can use it is three months.
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Used for
Dosage forms
  • Gel
  • Cream, gel, or ointment
  • Topical solution
Price
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Reviews
146 reviews so far
54%
saidit'sworth it
26%
saiditworked well
12%
saidit'sa big hassle

Have you used Benzamycin (benzoyl peroxide / erythromycin)?

Leave a review
93 reviews so far
46%
saidit'sworth it
34%
saiditworked well
19%
saidit'sa big hassle

Have you used Akne-Mycin (Erythromycin)?

Leave a review
Side effects
6possible side effects
  • Dry skin
    8%
  • Dryness
    3%
  • Hives
    3%
  • Reaction where applied
    3%
  • Eyelid inflammation
    2%
  • Itching
    2%
See more detailed side effects
1possible side effects
  • Burning
    25%
See more detailed side effects
Risks and risk factors
  • Bleaching effects
  • Skin irritation
    • Using other medicines or products that irritate the skin
    • Eczema
    • Extreme temperatures (hot or cold)
  • Allergic reaction
  • Development of more serious infections
    • Long-term use of Benzamycin (benzoyl peroxide / erythromycin)
  • Pregnancy and breastfeeding
See more detailed risks and warnings
  • Allergic reaction
  • Skin irritation
    • Using other medicines or products that irritate the skin
    • Eczema
    • Extreme temperatures (hot or cold)
  • Development of more serious infections
See more detailed risks and warnings