Compare benzoyl peroxide vs. Cleocin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats acne.

Benzac (benzoyl peroxide) is the most effective over-the-counter treatment for mild acne.

3.4/ 5 average rating with 394 reviewsforbenzoyl peroxide
Topical treatment for acne.

Cleocin T (Clindamycin Phosphate) is good for treating many bacterial infections and is available as a generic. If you're taking the vaginal form, you have to avoid sex and tampons for the period your doctor tells you to. The topical form can cause skin sensitivity and irritation.

3.5/ 5 average rating with 115 reviewsforCleocin
Upsides
  • Available over-the-counter from many brands.
  • Benzac (benzoyl peroxide) comes in many different forms and combinations with other acne products.
  • Available in generic.
  • Topical form treats acne.
  • Available in different oral forms: tablet, capsule, and suspension.
  • Available in forms to treat skin infections and vaginal infections.
  • Used to treat many types of bacterial infections.
  • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
  • Can be taken with or without food.
Downsides
  • Benzac (benzoyl peroxide) increases your skin's sensitivity to the sun and may also cause dryness or stinging.
  • Be careful when applying Benzac (benzoyl peroxide) to large areas since it can bleach hair, clothing, and pillow cases upon contact.
  • Benzac (benzoyl peroxide) needs to be combined with other medications to effectively treat severe acne.
  • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
  • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
  • If you're allergic to aspirin, your doctor may have to prescribe an alternate.
  • If you have to take live vaccines, talk to your doctor when to take them since Clindamycin can make it less effective.
  • If you're taking the topical form, it can cause sensitivity and irritation.
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Used for
Dosage forms
  • Cream
  • Lotion
  • Liquid
  • Gel
  • Foam
  • Soap
  • Topical
  • Cream, gel, or ointment
  • Foam
  • Vaginal cream
  • Vaginal suppository
  • Injection
Price
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Reviews
394 reviews so far
60%
saidit'sworth it
29%
saiditworked well
9%
saidit'sa big hassle

Have you used Benzac (benzoyl peroxide)?

Leave a review
115 reviews so far
57%
saidit'sworth it
43%
saiditworked well
19%
saidit'sa big hassle

Have you used Cleocin T (Clindamycin Phosphate)?

Leave a review
Side effects
The Benzac (benzoyl peroxide) FDA package insert doesn’t have numbers about how common side effects are.
The Cleocin T (Clindamycin Phosphate) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Bleaching
  • Skin irritation
    • Using other medicines or products that irritate the skin
    • Eczema
    • Extreme temperatures (hot or cold)
  • Allergic reaction
See more detailed risks and warnings
  • Diarrhea
  • Liver damage
    • History of liver disease
  • Rash
See more detailed risks and warnings