Compare Besivance vs. Zylet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats eye infections like pink eye.

Besivance (besifloxacin) effectively treats pink eye, especially more severe cases, but will cost more because no generic is currently available.

Treats certain eye inflammation and infections.

Zylet (loteprednol and tobramycin) is a good choice for certain eye infections and conditions, but isn't for everyone and you can't use it for a long time.

Upsides
  • Besivance (besifloxacin) effectively treats bacterial eye infections like pink eye, and is often chosen for more serious cases.
  • Less frequent applications make Besivance (besifloxacin) more convenient to use than similar medicines.
  • Has fewer side effects compared to alternative oral medications since Besivance (besifloxacin) is applied directly to the eyes.
  • Zylet (loteprednol and tobramycin) is very effective at reducing inflammation and treating infection in certain eye conditions.
  • Since Zylet (loteprednol and tobramycin) is applied directly into the eye, you won't experience any severe body side effects.
Downsides
  • Application of Besivance (besifloxacin) can temporarily irritate the eyes.
  • Using eye drops may be harder for some people compared to taking a pill.
  • Zylet (loteprednol and tobramycin) is expensive.
  • Taking Zylet (loteprednol and tobramycin) can be burdensome, as you have to use it multiple times a day.
  • There's a limit to how much Zylet (loteprednol and tobramycin) can be used.
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Used for
  • Steroid responsive eye inflammation conditions
  • Superficial eye infections
  • Blepharitis
Dosage forms
  • Eye drops
  • Eye drops
Price
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Reviews
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Side effects
4possible side effects
  • Red eye
    2%
  • Blurred vision
    2%
  • Eye irritation
    2%
  • Headache
    2%
See more detailed side effects
12possible side effects
  • Headache
    14%
  • Increased eye pressures
    10%
  • Eye burning
    9%
  • Eye stinging
    9%
  • Vision problems
    4%
  • Eye discharge
    4%
  • Eye itching
    4%
  • Tearing problems
    4%
  • Light sensitivity
    4%
  • Eye deposits
    4%
  • Eyelid problems
    4%
  • Other non-specific eye disorders
    4%
See more detailed side effects
Risks and risk factors
  • Allergy to ingredients
    • Allergies to quinolone antibiotics such as Levaquin and Cipro.
  • Risk for contamination
  • Not to be used with contact lenses
  • For use topically in the eyes only
  • Risk of infection
    • Prolonged use
See more detailed risks and warnings
  • Increased eye pressure
    • Taking Zylet (loteprednol and tobramycin) with other steroids
  • Cataracts
  • Delayed healing
    • Recent cataract surgery
    • Cornea problems
  • Second infections
    • Acute purulent eye infections
  • Allergic reaction
See more detailed risks and warnings