Compare Boniva vs. Minivelle
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Prevents bone loss.
Boniva (ibandronate) is a first-choice treatment for osteoporosis and is available as a generic, but how you have to take it can be a hassle. It's also only approved for women, not men.
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2.9/ 5 average rating with 64 reviewsforBoniva
Relieves menopause symptoms.
The Minivelle (estradiol patch) is the mini-me of estrogen patches. It's used twice a week, available in five strengths, and has the least amount of skin irritation.
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4.2/ 5 average rating with 17 reviewsforMinivelle
Upsides
- Available in generic.
- Available in pills that can be taken by mouth once a month.
- Also available as a shot given into your vein every 3 months.
- Minivelle (estradiol patch) is the smallest estrogen patch available. It's the size a dime and comes in 5 different strengths.
- Causes little or no skin irritation and doesn't leave much adhesive on your skin.
- Minivelle (estradiol patch) replaces estrogen to your whole body and relieves many symptoms due to low estrogen, like hot flashes and vaginal dryness.
- By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
- Lowers your risk of fractures by keeping your bones healthy.
Downsides
- You have to take Boniva (ibandronate) first thing in the morning with a full glass of water.
- You have to remain upright for at least 60 minutes after you take the medicine, which can be a problem if you have mobility issues.
- It is only approved to treat and prevent osteoporosis in women who have gone through menopause.
- You need to replace Minivelle (estradiol patch) twice a week, compared to other patches that are once a week.
- Patches can fall off.
- Increases your risk of uterine and breast cancer.
- Increases your risk of developing blood clots and stroke.
- Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
- Can't be used in people with liver problems.
Used for
- Hot flashes
- Prevention of bone thinning in postmenopausal women
Dosage forms
- Pill
- Injection
- Patch
Price
Lowest price
$24.49
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$32.19
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Reviews
64 reviews so far
31%
saidit'sworth it
20%
saiditworked well
27%
saidit'sa big hassle
Have you used Boniva (ibandronate)?
Leave a review17 reviews so far
82%
saidit'sworth it
76%
saiditworked well
18%
saidit'sa big hassle
Have you used Minivelle (estradiol patch)?
Leave a reviewSide effects
22possible side effects
- Abdominal pain8%
- High blood pressure6%
- Indigestion6%
- Joint pain6%
- Nausea5%
- Diarrhea5%
- Back pain5%
- Constipation4%
- Pain in arms or legs4%
- Flu4%
- Cold4%
- Localized joint stiffness and pain3%
- Bronchitis3%
- Headache3%
- Influenza-like illness3%
- Muscle pain2%
- Muscle cramp2%
- Urinary tract infection2%
- Upper respiratory tract infection2%
- Dizziness2%
- Rash2%
- Sleep difficulty2%
20possible side effects
- Headache26%
- Breast pain13%
- Back pain11%
- Menstrual bleeding11%
- Influenza8%
- Common cold8%
- Nausea5%
- Pain5%
- Sinus infection5%
- Lung infection5%
- Neck pain5%
- Limb pain5%
- Sinus congestion5%
- Joint pain4%
- Depression3%
- Constipation2%
- Flu-like symptoms2%
- Sinus headache2%
- Anxiety2%
- Trouble sleeping2%
Risks and risk factors
- Irritation and ulcers to the stomach and esophagus
- Taking with aspirin or other NSAIDS (nonsteroidal anti-inflammatory drugs)
- History of ulcers, or other stomach or esophageal problems
- History of difficulty swallowing
- Unable to sit upright or stand for 60 minutes after taking the medicine
- Pain in the bones and/or muscles
- Problems in the jawbone
- Oral or dental surgery
- Cancer
- Poor oral hygiene
- Prolonged use of Boniva (ibandronate)
- Leg bone fractures
- Low calcium in the blood
- History of low calcium in the blood
- Endometrial cancer
- Using estrogen for more than one year
- Breast cancer
- Personal or family history of breast cancer
- Using estrogen for more than one year
- Increased risk of blood clots and stroke
- Personal or family history of blood clots
- Smoking
- Obesity
- Systemic lupus erythematosus (SLE)
- Increased risk of heart disease
- Smoking
- Obesity
- High blood pressure
- High blood sugar
- High cholesterol
- Age 50 or older
- Dementia
- Age 65 or older
- Pancreas swelling (pancreatitis)
- High levels of triglycerides