Compare brimonidine vs. Combigan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Lowers high eye pressure.

Alphagan P (brimonidine) is an effective medication for treating high pressure in the eyes, but it can cause some bothersome effects such as dry mouth, eye burning, and stinging upon administration.

An eyedrop used to treat increased pressure inside the eye

An effective control of high pressure within the eye when used alone or with other eye medications. Lowering eye pressure back to normal can prevent the onset of glaucoma.

Upsides
  • Alphagan P (brimonidine) is a good medication for reducing high eye pressure and helping prevent development of glaucoma.
  • It is available as a cheaper, generic form.
  • The two medicines do not have to be taken separately
Downsides
  • Even though it's administered in the eye, Alphagan P (brimonidine) can make you feel fatigued and drowsy.
  • You must wait 5 minutes before using another eye drop in the same eye.
  • You have to remove contact lenses and leave them out for 15 minutes after using the eyedrops.
  • Alphagan P (brimonidine) can't be used in children under 2 years of age.
  • The medicine is absorbed into your body and therefore may react to other conditions you have, such as heart or lung conditions
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Used for
  • Elevated intraocular pressure
  • Glaucoma
  • In patients requiring adjunctive or replacement therapy Ocular hypertension
  • In patients requiring adjunctive or replacement therapy
Dosage forms
  • Eye drops
  • Eye drops
Price
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Reviews
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Side effects
The Alphagan P (brimonidine) FDA package insert doesn’t have numbers about how common side effects are.
The Combigan (Brimonidine / Timolol) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Contact lens use
  • Contamination of eye products after use
    • Corneal disease
    • Disruption of the ocular epithelial surface
  • Severe heart disease
  • CNS depression (sleepiness and fatigue)
See more detailed risks and warnings
  • Heart problems (Cardiovascular Risk)
    • High blood Pressure
    • irregular heart beats
  • Lung conditions
    • People with Asthma, COPD, or other breathing conditions
  • Redness in eye
    • Long term use
  • Visual Changes
  • Young children
See more detailed risks and warnings