Compare Bumex vs. spironolactone

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Bumex (bumetanide)

Prescription only
Lowers blood pressure.

Bumex (bumetanide) is very good in lowering blood pressure. However, it can make you dehydrated and lower your blood pressure too much.

Removes extra water from your body.

Aldactone (spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.

  • Available in generic.
  • Much stronger than other water pills.
  • Has a low risk of causing muscle problems from low potassium levels in your blood.
  • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
  • Can lower blood pressure.
  • Reduces the risk of death in people with heart failure.
  • People taking Bumex (bumetanide) might urinate more often.
  • Bumex (bumetanide) can cause dehydration and loss of salts in your body.
  • People with allergies to sulfa-containing medicines should not take Bumex (bumetanide).
  • Blood tests should be done regularly to check your potassium and other salts.
  • Aldactone (spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
  • Has many possible side effects, especially when higher doses are used.
  • Can increase the risk of tumor growth.
  • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
Used for
Dosage forms
  • Pill
  • Injection
  • Pill
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Not enough review data.Leave a review
Not enough review data.Leave a review
Side effects
3possible side effects
  • High uric acid in blood
  • Low potassium
  • High blood sugar
See more detailed side effects
The Aldactone (spironolactone) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Dehydration and loss of salts in the blood
    • Age 65 or older
    • Having severe diarrhea
  • Severe allergic reactions
    • History of sulfa allergy
  • Hearing problems
    • Kidney disease
    • High dose of Bumex (bumetanide)
  • Kidney problems
    • Difficulty urinating
    • Kidney disease
  • More severe side effects
    • Over age 65
See more detailed risks and warnings
  • Tumor development
  • Low blood pressure
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
  • Heart problems from high potassium
    • Current kidney problems
    • Taking other medicines that increase potassium
    • Use of salt substitutes
  • Breast pain or swelling
See more detailed risks and warnings