Compare Buspar vs. Oleptro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT

Buspar (buspirone)

Prescription only

Oleptro (Trazodone)

Prescription only
Helps you relax.

Buspar (buspirone) relieves anxiety with less drowsiness and abuse potential than other anti-anxiety medicines, but it takes time to work and effects might wear off over time.

3.4/ 5 average rating with 67 reviewsforBuspar
Improves mood and helps you sleep.

Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.

3.6/ 5 average rating with 59 reviewsforOleptro
Upsides
  • Doesn't cause as much physical dependence or withdrawal symptoms as other medications used for anxiety.
  • Available as a generic, which is cheaper.
  • Tablets can be split for easy dose changes.
  • Doesn't cause as much drowsiness as other medications for anxiety.
  • Commonly used in lower doses to help treat sleep problems (insomnia).
  • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
  • Fewer sexual side effects than many other antidepressants.
  • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
  • Comes as a generic medication and is cheaper than many other sleep aides.
  • Six out of ten people who use an antidepressant for the first time find that it works for them.
Downsides
  • Not for quick relief of anxiety symptoms since Buspar (buspirone) can take as long as 4 weeks to fully work.
  • Not as effective for short-term anxiety conditions or panic disorders.
  • Some people find that Buspar (buspirone) loses effectiveness over long periods of time.
  • Must take Buspar (buspirone) twice daily for full effect.
  • Not as effective as other medications for depression.
  • More sedating than other antidepressants.
  • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
  • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
ADVERTISEMENT
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
67 reviews so far
46%
saidit'sworth it
45%
saiditworked well
22%
saidit'sa big hassle

Have you used Buspar (buspirone)?

Leave a review
59 reviews so far
73%
saidit'sworth it
49%
saiditworked well
24%
saidit'sa big hassle

Have you used Oleptro (Trazodone)?

Leave a review
Side effects
19possible side effects
  • Dizziness
    12%
  • Drowsiness
    10%
  • Nausea
    8%
  • Headache
    6%
  • Nervousness
    5%
  • Fatigue
    4%
  • Trouble sleeping
    3%
  • Lightheadedness
    3%
  • Dry mouth
    3%
  • Worse concentration
    2%
  • Excitement
    2%
  • Anger/hostility
    2%
  • Confusion
    2%
  • Depression
    2%
  • Blurred vision
    2%
  • Upset stomach
    2%
  • Diarrhea
    2%
  • Numbness
    2%
  • Weakness
    2%
See more detailed side effects
29possible side effects
  • Somnolence/Sedation
    46%
  • Drowsiness
    41%
  • Dry Mouth
    34%
  • Headache
    33%
  • Dizziness/Lightheadedness
    28%
  • Dry mouth
    25%
  • Dizziness
    25%
  • Nausea
    21%
  • Blurred Vision
    15%
  • Fatigue
    15%
  • Nausea/Vomiting
    13%
  • Diarrhea
    9%
  • Constipation
    8%
  • Skin Condition/Edema
    7%
  • Weight Loss
    6%
  • Nasal/Sinus Congestion
    6%
  • Abdominal/Gastric Disorder
    6%
  • Syncope
    5%
  • Musculoskeletal Aches/Pains
    5%
  • Tremors
    5%
  • Nightmares/Vivid Dreams
    5%
  • Weight Gain
    5%
  • Back pain
    5%
  • Vision blurred
    5%
  • Sexual dysfunction
    5%
  • Hypotension
    4%
  • Incoordination
    2%
  • Ejaculation disorders
    2%
  • Decreased libido
    2%
See more detailed side effects
Risks and risk factors
  • Higher blood pressure
    • Taking Buspar (buspirone) with MAOIs
    • Taking Buspar (buspirone) within 14 days after stopping a MAOIs
  • Serotonin syndrome
    • Taking other medicines that affect serotonin levels
  • Withdrawal symptoms from other anti-anxiety medicines
    • Stopping benzodiazepines suddenly
See more detailed risks and warnings
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • Seizures
    • History of seizures
    • Alcoholism
    • Eating disorder
    • Higher dose
    • Drug interactions
  • Painful erection
  • Low blood pressure
    • Age 65 years or older
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings