Compare Byetta vs. Glucovance
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood sugar.
Byetta (Exenatide) can lower your blood sugars in addition to metformin. It does not increase your appetite unlike some other anti-diabetics, but must be given by injection and usually causes upset stomach.
Lowers blood sugar.
Glyburide / Metformin is an effective combination medicine for lowering blood sugar, but it is likely to cause diarrhea in the first few weeks.
Upsides
- Can lower your A1c (average blood sugar over time) by 1%.
- Not as likely to cause very low blood sugar as glyburine or insulin.
- Does not increase your appetite like other anti-diabetic medicines.
- Pen is dialed to a single dose for easy injections.
- Glyburide / Metformin effectively lowers blood sugar levels more so than if each of the individual medicines it contains are taken alone.
- Protects your organs and blood vessels from the harmful effects of high blood sugar levels.
- Can potentially lower your "bad cholesterol" levels.
- Glyburide / Metformin is available in a generic form and is cheaper than many other combination diabetes medicines.
Downsides
- Byetta (Exenatide) must be injected twice a day. Other medicines like it can be injected once daily or even weekly.
- It commonly causes nausea, vomiting, diarrhea, constipation, or indigestion.
- Can affect how well your antibiotics and birth control pills work. Take them no sooner than one hour after your injections.
- Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
- Glyburide / Metformin is likely to cause nausea, stomach upset, or diarrhea in the first few weeks.
- Not a good treatment option for those with kidney and/or liver problems.
- Drinking large amounts of or frequently using alcohol while taking Glyburide / Metformin can cause harm to your body.
- Can cause some weight gain.
Used for
Dosage forms
- Injection
- Pill
Price
No pricing information available
Lowest price
$12.77
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Reviews
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Side effects
6possible side effects
- Upper respiratory infection17%
- Diarrhea17%
- Headache9%
- Nausea/vomiting8%
- Stomach pain7%
- Dizziness6%
Risks and risk factors
- Loss of medication effectiveness
- Pancreatitis
- Kidney problems
- Severe renal impairment
- End-stage renal disease
- Serious stomach problems
- Severe gastrointestinal disease
- Gastroparesis
- Low blood sugar (hypoglycemia)
- Lactic acid build up in blood
- History of kidney problems
- History of liver problems
- Those with congestive heart failure
- Using contrast dye for procedures
- Undergoing surgery
- Drinking large amounts or frequent use of alcohol
- Serious heart problems
- Low blood sugar
- Skipping meals or having inconsistent meal times
- Drinking alcohol
- Using other blood sugar-lowering medicine
- People age 60 or older
- Those with kidney and/or liver problems
- Severe allergic reaction
- History of allergy to sulfa-containing medicine
- Breakdown of red blood cells
- People with G6PD deficiency