Compare Calan vs. Lisinopril

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Calan (Verapamil)

Prescription only

Zestril (lisinopril)

Prescription only
Lowers blood pressure and controls heart rate.

Verapamil works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling.

2.9/ 5 average rating with 43 reviewsforCalan
Lowers blood pressure.

Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.

3.8/ 5 average rating with 687 reviewsforLisinopril
Upsides
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Very cheap drug, and comes available as a liquid for children over 6 years of age.
Downsides
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Verapamil than men.
  • You can't miss doses. Stopping Verapamil suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not a good medication for you if you drink alcohol.
  • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Zestril (lisinopril) isn't safe to use if you're pregnant.
  • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Delayed release capsule
  • Pill
  • Liquid
Price
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Reviews
43 reviews so far
35%
saidit'sworth it
33%
saiditworked well
21%
saidit'sa big hassle

Have you used Calan (Verapamil)?

Leave a review
687 reviews so far
61%
saidit'sworth it
51%
saiditworked well
14%
saidit'sa big hassle

Have you used Zestril (lisinopril)?

Leave a review
Side effects
5possible side effects
  • Constipation
    7%
  • Headache
    5%
  • Dizziness
    4%
  • Lethargy
    3%
  • Dyspepsia
    3%
See more detailed side effects
1possible side effects
  • Low blood pressure
    5%
See more detailed side effects
Risks and risk factors
  • Heart failure
    • Severe left ventricular dysfunction (ejection fraction <30%)
    • Taking beta-blockers
  • Low blood pressure
  • Elevated liver enzymes
    • History of liver disease
  • Heart rhythm problems
    • History of kidney disease
    • History of liver disease
See more detailed risks and warnings
  • Harm to fetus
    • Women of childbearing age
  • Cough
  • Swelling of face and head
    • African descent
  • High potassium
    • Current kidney problems
    • Medicines that increase potassium
    • Use of salt substitutes
  • Worsening kidney problems
    • History of kidney problems
  • Low blood pressure
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
See more detailed risks and warnings